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2-PHTHALIMIDOETHYL PHOSPHORODICHLORIDATE is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

52198-45-5

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52198-45-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 52198-45-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,1,9 and 8 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 52198-45:
(7*5)+(6*2)+(5*1)+(4*9)+(3*8)+(2*4)+(1*5)=125
125 % 10 = 5
So 52198-45-5 is a valid CAS Registry Number.

52198-45-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(2-dichlorophosphoryloxyethyl)isoindole-1,3-dione

1.2 Other means of identification

Product number -
Other names 2-PHTHALIMIDOETHYL PHOSPHORODICHLORIDATE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:52198-45-5 SDS

52198-45-5Relevant academic research and scientific papers

Amplification of a FRET Probe by Lipid–Water Partition for the Detection of Acid Sphingomyelinase in Live Cells

Pinkert, Thomas,Furkert, David,Korte, Thomas,Herrmann, Andreas,Arenz, Christoph

supporting information, p. 2790 - 2794 (2017/02/26)

Real-time monitoring of acid sphingomyelinase (ASM) activity is crucial for investigating its role in lipid-mediated signaling processes. In this study, we synthesized fluorescent phosphosphingolipids capable of FRET by phosphorodichloridate chemistry. These sphingomyelin analogues are substrates for recombinant human ASM and can be used to monitor ASM activity by fluorescence spectroscopy. Incubation with cell lysates from wild-type and knock-out mice further confirmed probe cleavage to be exclusive to ASM. We also systematically exploited the environmental sensitivity of the fluorophores to achieve significant increases in responsiveness. This concept may be transferred to other lipid probes in the future. The ASM activity in live cells was imaged by two-photon-excitation microscopy.

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