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N-desmethyl-chlorprothixen is a chemical compound that is a major metabolite of the antipsychotic drug chlorprothixene. It is formed in the liver through the process of demethylation, which involves the removal of a methyl group from the parent compound. This metabolite retains some of the pharmacological properties of the original drug, including its effects on dopamine and serotonin receptors in the brain. As a result, N-desmethyl-chlorprothixen contributes to the overall therapeutic and side effects of chlorprothixene, which is used to treat various psychiatric disorders such as schizophrenia and bipolar disorder. The presence of this metabolite in the body can influence the duration and intensity of the drug's action, as well as its potential for drug interactions and side effects.

522-22-5

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522-22-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 522-22-5 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,2 and 2 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 522-22:
(5*5)+(4*2)+(3*2)+(2*2)+(1*2)=45
45 % 10 = 5
So 522-22-5 is a valid CAS Registry Number.

522-22-5Upstream product

522-22-5Downstream Products

522-22-5Relevant academic research and scientific papers

Bacterial Biosynthetic P450 Enzyme PikCD50N: A Potential Biocatalyst for the Preparation of Human Drug Metabolites

Cheng, Fangyuan,Du, Lei,Durairaj, Pradeepraj,Guo, Jiawei,Li, Fengwei,Li, Shengying,Liu, Xiaohui,Long, Xiangtian,Ma, Li,Tang, Dandan,Zhang, Gang,Zhang, Wei,Zhang, Xingwang

, p. 14563 - 14571 (2021/11/12)

Human drug metabolites (HDMs) are important chemicals widely used in drug-related studies. However, acquiring these enzyme-derived and regio-/stereo-selectively modified compounds through chemical approaches is complicated. PikC is a biosynthetic P450 enz

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