5221-66-9

Upstream product

• 1871-76-7 diphenylacetic acid chloride 
• 15430-52-1 prop-2-yn-1-amine hydrochloride 
• 2450-71-7 Propargylamine 

Downstream Products

• 1273533-37-1 2-(2-benzhydryl-5-methyl-imidazol-1-yl)pyridine 
• 1273533-35-9 2-benzhydryl-5-methyl-1-phenyl-1H-imidazole 
• 5221-68-1 N-Acetonyl-diphenyl-essigsaeure-amid 
• 52829-67-1 2-benzhydryl-5-methyl-oxazole 

Relevant academic research and scientific papers

A novel Zn-catalyzed hydroamination of propargylamides: A general synthesis of di- and tri-substituted imidazoles

Starting from commercially available amines and propargylamides a variety of substituted imidazoles were synthesized via a novel hydroamination- cyclization sequence. The target compounds are obtained in good to excellent yields in the presence of catalytic amounts of zinc triflate.

Method for treating conditions related to the glutamate receptor using carboxylic acid amide derivatives

The present invention is concerned with the use of carbonylamino derivatives of the formula wherein R signifies lower alkyl, lower alkenyl, lower alkinyl, cycloalkyl, lower alkoxy or CF3; R1signifies hydrogen or lower alkyl; R2and R3signify, independently from each other, hydrogen, halogen or nitro; Y signifies CH or N; n is 0-6; m is 0-2; as well as with their pharmaceutically acceptable salts for the treatment of diseases, which relate to metabotropic glutamate receptor antagonists and/or agonists.