52260-30-7 Usage
General Description
2-(Methylthio)phenyl isocyanate is a chemical compound used primarily in the chemical industry. It is an organosulfur compound which is characterized by the presence of a methylthio group and an isocyanate group attached to a phenyl ring. The chemical formula of 2-(Methylthio)phenyl isocyanate is C8H7NOS. It may be used in the synthesis of various organic materials due to its reactivity towards nucleophiles. This chemical is dangerous to handle due to its toxic and corrosive properties. Its vapors may cause respiratory irritation and eye damage. Proper safety measures should be taken while handling this chemical.
Check Digit Verification of cas no
The CAS Registry Mumber 52260-30-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,2,6 and 0 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 52260-30:
(7*5)+(6*2)+(5*2)+(4*6)+(3*0)+(2*3)+(1*0)=87
87 % 10 = 7
So 52260-30-7 is a valid CAS Registry Number.
InChI:InChI=1/C8H7NOS/c1-11-8-5-3-2-4-7(8)9-6-10/h2-5H,1H3
52260-30-7Relevant articles and documents
5-Hydroxytryptamine (5-HT3) Receptor Antagonists. 3. Ortho-Substituted Phenylureas
Bermudez, Jose,Dabbs, Steven,King, Frank D.
, p. 1932 - 1935 (2007/10/02)
A novel series of potent 5-HT3 receptor antagonists, ortho-substituted phenylureas 6a-z, is described in which the 5-membered ring of the previously reported indazoles and indolines has been replaced by an intramolecular hydrogen bond.High potency was found both for carbamate 6a and urea 6b.Granatane 6c was less potent than the equivalent tropane.Phenylurea 11c lacking the ortho substituent was inactive.Whereas further substitution could not be tolerated in the aromatic ring, activity was retained with a range of O-alkyl groups, compounds 6k-t.In addition, good activity was found for ortho ester 6u and sulfonamide 6x.The ortho-substituted phenylureas can therefore be regarded as bioisosteres of the 6,5-heterocycles indole, indazole, and indoline.
