52260-49-8Relevant articles and documents
Noteworthy observations accompanying synthesis of the apoptolidin disaccharide
Srinivasarao, Madduri,Park, Taesik,Chen, Yuzhong,Fuchs, Philip L.
, p. 5858 - 5860 (2011/07/08)
A stereoselective synthesis of the apoptolidin disaccharide is reported. The key chemistry features a new transformation utilizing a highly selective tetramethylalkoxyalanate[v]-directed syn-methylation of a vinylogous ester, isolation of a hydrate of a 2-keto sugar, an eco-friendly radical cleavage of a bromomethyl group, and an efficient preparation of a fluorodisaccharide via the use of XtalFluor-E.