522607-97-2Relevant academic research and scientific papers
Modeling the Adenosine Receptors: Comparison of the Binding Domains of A2A Agonists and Antagonists
Kim, Soo-Kyung,Gao, Zhan-Guo,Van Rompaey, Philippe,Gross, Ariel S.,Chen, Aishe,Van Calenbergh, Serge,Jacobson, Kenneth A.
, p. 4847 - 4859 (2003)
A three-dimensional model of the human A2A adenosine receptor (AR) and its docked ligands was built by homology to rhodopsin and validated with site-directed mutagenesis and the synthesis of chemically complementary agonists. Different binding
