522622-95-3

Basic information

• Product Name: Benzenemethanol, 3-(methoxymethyl)-
• CAS NO: 522622-95-3
• Molecular Formula: C9H12O2
• Molecular Weight: 152.193
• Mol File: 522622-95-3.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzenemethanol, 3-(methoxymethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, 3-(methoxymethyl)-(522622-95-3)
• EPA Substance Registry System: Benzenemethanol, 3-(methoxymethyl)-(522622-95-3)

Safety Data

• Hazardous Substances Data: 522622-95-3(Hazardous Substances Data)

Usage

Chemical compound

Benzenemethanol, 3-(methoxymethyl)-

Also known as

3-(Methoxymethyl)phenylmethanol

Physical properties

Colorless liquid with a mild, floral odor

Main use

Fragrance and flavoring agent in consumer products

Other uses

Synthesis of pharmaceuticals, solvent in organic reactions

Health hazards

Exposure to high concentrations can cause irritation to skin, eyes, and respiratory system

Safety precautions

Handling with caution is important

Upstream product

• 1515-87-3 methyl 3-(methoxymethyl)benzoate 
• 1129-28-8 3-methoxycarbonylbenzyl bromide 
• 1515-86-2 (3-Cyanophenyl)methyl methyl ether 
• 823-78-9 meta-bromobenzyl bromide 
• 626-18-6 1,3-dimethanol benzene 
• 74-88-4 methyl iodide 
• 32194-76-6 3-methoxymethyl-benzoic acid 
• 1515-89-5 3-(methoxymethyl)bromobenzene 

Downstream Products

• 119858-82-1 m-chloromethyl(methoxymethyl)benzene 
• 125604-03-7 1-(bromomethyl)-3-(methoxymethyl)benzene 
• 1233560-86-5 methyl 2-[3-(methoxymethyl)benzyl]-3-oxobutanoate 
• 148278-90-4 1-{3-[(methyloxy)methyl]phenyl}methanamine 

Relevant articles and documents

DERIVATIVES OF 2-PYRIDIN-2-YL-PYRAZOL-3(2H)-ONE, PREPARATION AND THERAPEUTIC USE THEREOF AS HIF ACTIVATORS

The present invention relates to novel substituted dihydropyrazolone derivatives, to their preparation and to their therapeutic use as activators of the transcription factor HIF.

COMPOUNDS WHICH INHIBIT BETA-SECRETASE ACTIVITY AND METHODS OF USE THEREOF

The present invention provides novel beta-secretase inhibitors of the general formula (I), where the variables A1, A2, L1, L2, L3, R1, R2, R3, R4, R5, R6 and R7 are as defined in the claims, a method for their use in treating Alzheimer's disease, and methods for their use in reducing memapsin 2 catalytic activity.

Synthesis of radiolabeled O6-benzylguanine derivatives as new potential PET tumor imaging agents for the DNA repair protein O6-alkylguanine-DNA alkyltransferase

Novel radiolabeled O6-benzylguanine derivatives, 2-amino-6-O-[11C]-[(methoxymethyl)benzyloxy]-9-benzyl purines ([11C]p-O6AMBP, 1a; [11C]m-O6-AMBP, 1b; [11C]o-O6-AMBP, 1c), have been synthesized for evaluation as new potential positron emission tomography (PET) tumor imaging agents for the DNA repair protein, O6-alkylguanine-DNA alkyltransferase (AGT). The appropriate precursors for radiolabeling were obtained in three steps from starting material 2-amino-6-chloropurine with moderate to excellent chemical yields. Tracers were prepared by O-[11C]methylation of hydroxymethyl precursors using [11C]methyl triflate. Pure target compounds were isolated by solid-phase extraction (SPE) purification procedure in 45-60% radiochemical yields (decay corrected to the end of bombardment), and a synthesis time of 20-25 min. Copyright