125604-03-7

Upstream product

• 124-41-4 sodium methylate 
• 626-15-3 1,3-bis-(bromomethyl)benzene 
• 522622-95-3 3-(methoxymethyl)benzyl alcohol 
• 1515-87-3 methyl 3-(methoxymethyl)benzoate 
• 1129-28-8 3-methoxycarbonylbenzyl bromide 

Downstream Products

• 28746-20-5 3-(methoxymethyl)benzaldehyde 
• 1277173-50-8 C₆H₄(CH₂OCH₃)(CH₂P(C(CH₃)3)2) 
• 1233560-86-5 methyl 2-[3-(methoxymethyl)benzyl]-3-oxobutanoate 
• 875542-05-5 C₁₈H₂₆O₆ 
• 72985-28-5 3,5'-Bis(methoxymethyl)-2'-methyldeoxybenzoin trimethylene dithioketal 
• 72985-00-3 3,5'-Bis(brommethyl)-2'-methyldeoxybenzoin trimethylene dithioketal 
• 72984-98-6 3,5'-Bis(methoxymethyl)-2'-methyldeoxybenzoin 
• 72984-99-7 3,5'-Bis(bromomethyl)-2'-methyldeoxybenzoin 
• 73502-06-4 m-(Methoxymethyl)benzaldehyde trimethylene dithioacetal 

Relevant academic research and scientific papers

DERIVATIVES OF 2-PYRIDIN-2-YL-PYRAZOL-3(2H)-ONE, PREPARATION AND THERAPEUTIC USE THEREOF AS HIF ACTIVATORS

The present invention relates to novel substituted dihydropyrazolone derivatives, to their preparation and to their therapeutic use as activators of the transcription factor HIF.

Syntheses and characterization of palladium complexes with a hemilabile "pCO" pincer ligand

The synthesis of a new pincer ligand (tBuPCO = 2-(CH 2PtBu2)-6-(CH2OCH3)C 6H3) is reported. This ligand has been observed to coordinate in three different modes to pal

Microbial Stereodifferentiating Reduction of (+/-)4-Methyl- and (+/-)-6-Methyl-1-oxometacyclophanes and Revision of the Absolute Configuration of 4-Substituted Metacyclophanes

Partial oxidative hydrolysis of 4-bromo-1,1,10,10-bis(trimethylenedithio)metacyclophane (7) yielded the bromo ketones 8 and 9 which were respectively converted into (+/-)-4-methyl- (3) and (+/-)-6-methyl-1-oxometacyclophanes (4).The unambiguous synthesis of (+/-)-3 from 2,5-dimethylbenzoic acid (18) assigned their structures.Incubation of (+/-)-3 with Rhodotorula rubra gave a mixture of (-)-ketone 3, (-) axial alcohol 38, and (-) equatorial alcohol 39.The observed (-) Cotton effect indicated the pS configuration of (-)-3, and transformation of (-)-3 into (+)-4-methylmetacyclophane (5) permitted the assignment of the pR configuration to (+)-5, opposite to Schloegl's proposal.This conclusion was further supported by the parallel sequence of the steps starting from (+/-)-6-methyl ketone.