52267-81-9Relevant academic research and scientific papers
PROSTANOIDS. XXVII. SOME ASPECTS OF CHEMO- AND STEREOSELECTIVE REDUCTION OF 7α-HYDROXY-6β-(3-OXO-4-m-CHLOROPHENOXY-1E-BUTENYL)-2-OXABICYCLOOCTAN-3-ONE
Miftakhov, M. S.,Vostrikov, N. S.,Kuznetsov, O. M.,Singizova, V. R.,Kuchin, A. V.,Tolstikov, G. A.
, p. 851 - 856 (2007/10/02)
The chemoselective reduction of 7α-hydroxy-6β-(3-oxo-4-m-chlorophenoxy-1E-butenyl)-2-oxabicyclooctan-3-one with respect to the oxo group was studied by means of readily obtainable reagents based on boron and aluminum.The optimum stereoselectivity of reduction was obtained with the use of diisobutylaluminum 2,6-di-tert-butyl-4-methylphenoxide in methylene chloride at -78 deg C.
