5227-53-2

Usage

Uses

Used in Polymerization Inhibition:
1-ALLYL-2-(2-HYDROXYETHYL)THIOUREA is used as a chain transfer agent in the polymerization of vinyl monomers for controlling the molecular weight and branching of the resulting polymers, ensuring the production of polymers with desired characteristics.
Used in ABS Resin Production:
In the plastics industry, 1-ALLYL-2-(2-HYDROXYETHYL)THIOUREA is used as a stabilizer in the production of acrylonitrile butadiene styrene (ABS) resins, contributing to the stability and quality of the final product.
Used in Rubber and Plastic Manufacturing:
1-ALLYL-2-(2-HYDROXYETHYL)THIOUREA is utilized as an additive in rubber and plastic manufacturing, enhancing the properties of these materials and improving their performance in various applications.
Used in Pharmaceutical and Medical Applications:
In the field of medicine, 1-ALLYL-2-(2-HYDROXYETHYL)THIOUREA is used as a radical scavenger and antioxidant, playing a crucial role in protecting biological systems from oxidative stress and damage, which can be beneficial in the treatment and prevention of various diseases and conditions.

Upstream product

• 502-42-1 cycloheptanone 
• 673-66-5 7-amino-heptanoic acid lactam 
• 2158-31-8 cycloheptanone oxime 
• 32566-60-2 3-chlorohexahydroazocin-2(1H)-one 
• 1340116-86-0 aza-cycloheptane-7-carboxylic acid tert-butyl ester 
• 26228-96-6 3,3-dichlorohexahydroazocin-2(1H)-one 

Downstream Products

• 869307-76-6 N-benzyloxycarbonyl-(2S)-aminobutyryl-(2R/S)-perhydroazepinecarboxylic acid 
• 869307-77-7 N-benzyloxycarbonyl-(2S)-aminobutyryl-(2R/S)-perhydroazepinecarboxylic acid n-butylamide 
• 5228-33-1 methyl azepane-2-carboxylate 
• 1034708-26-3 (R)-1-(tert-butoxycarbonyl)-azepane-2-carboxylic acid 
• 1034708-26-3 1-(tert-butoxycarbonyl)-azepane-2-carboxylic acid 
• 155905-76-3 (2S)-1-(tert-butoxycarbonyl)-2-azepanecarboxylic acid 
• 66865-37-0 (S)-perhydro-2-azepinecarboxylic acid 

Relevant academic research and scientific papers

Polybasic nitrogen heterocyclic non-natural chiral amino acid and synthesis method thereof

The invention relates to a polybasic nitrogen heterocyclic non-natural chiral amino acid and a synthesis method thereof. The amino acid can be applied to molecule building for antibiotic synthesis. According to the synthesis method, 2-aminodiethyl malonate and halogenated alkanes carry out substitution reactions, cyclization reactions, and decarboxylation reactions, and the reaction products are split to obtain the polybasic nitrogen heterocyclic non-natural chiral amino acid. The provided novel synthesis method has the advantages of simple synthesis route, low cost, convenient operation, andeasiness for commercial production, the chiral purity of obtained products is high, and the application prospect is good.

PTERIDINONES AS INHIBITORS OF POLO - LIKE KINASE

The present invention provides compounds having a structure according to Formula (I) or a salt or solvate thereof, wherein ring A, X, R1, R2, R3, R4, R5 and R6, are defined herein. The invention further provides pharmaceutical compositions including the compounds of the invention and methods of making and using the compounds and compositions of the invention, e.g., in the treatment and prevention of various disorders, such as Parkinson's disease.

Inhibitors of tripeptidyl peptidase II. 3. Derivation of butabindide by successive structure optimizations leading to a potential general approach to designing exopeptidase inhibitors

The cholecystokinin-8 (CCK-8)-inactivating peptidase is a serine peptidase that has been shown to be a membrane-bound isoform of tripeptidyl peptidase II (EC 3.4.14.10). It cleaves the neurotransmitter CCK-8 sulfate at the Met-Gly bond to give Asp-Tyr(SO