52273-55-9Relevant articles and documents
Discovery of Reversible Inhibitors of KDM1A Efficacious in Acute Myeloid Leukemia Models
Romussi, Alessia,Cappa, Anna,Vianello, Paola,Brambillasca, Silvia,Cera, Maria Rosaria,Dal Zuffo, Roberto,Fagà, Giovanni,Fattori, Raimondo,Moretti, Loris,Trifirò, Paolo,Villa, Manuela,Vultaggio, Stefania,Cecatiello, Valentina,Pasqualato, Sebastiano,Dondio, Giulio,So, Chi Wai Eric,Minucci, Saverio,Sartori, Luca,Varasi, Mario,Mercurio, Ciro
supporting information, p. 754 - 759 (2020/03/04)
Lysine-specific demethylase 1 (LSD1 or KDM1A) is a FAD-dependent enzyme that acts as a transcription corepressor or coactivator by regulating the methylation status of histone H3 lysines K4 and K9, respectively. KDM1A represents an attractive target for c
Visible Light-Mediated Conversion of Alcohols to Bromides by a Benzothiadiazole-Containing Organic Photocatalyst
Li, Run,Gehrig, Dominik W.,Ramanan, Charusheela,Blom, Paul W. M.,Kohl, Fabien F.,Wagner, Manfred,Landfester, Katharina,Zhang, Kai A. I.
, p. 3852 - 3859 (2019/07/15)
The search for metal-free, stable and high effective photocatalysts with sufficient photo-redox potentials remains a key challenge for organic chemists. Here, we present a benzothiadiazole-containing molecular organic photocatalyst with redox potentials of ?1.30 V and +1.64 V vs. SCE. The singlet state lifetime is 13 ns. Direct conversion from aliphatic alcohols to bromides has been conducted with the designed organic photocatalyst under visible light irradiation with high efficiency and selectivity. The catalytic efficiency of the novel benzothiadiazole-based photocatalyst is comparable with the state-of-art metal and non-metal catalysts. Furthermore, advanced photophysical studies including time-resolved photoluminescence and transient absorption spectroscopy offer a powerful support for photo-induced electron transfer from photocatalyst to the reactive substrates. Lastly, no photo-bleaching effect is observed, demonstrating the high stability and recyclable of the designed organic photocatalyst. (Figure presented.).
Diphenyl sulfate derivatives, preparation method of thereof and fluorophore sensor comprising thereof
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Paragraph 0236-0239, (2017/06/02)
The present invention relates to a diphenyl sulfate derivative, a method for preparing the same, and a fluorescence bio-sensor comprising the same. The diphenyl sulfate derivative having a novel structure according to the present invention traces cells and carries out immuno-fluorescence staining of the mitochondria of the cells satisfactorily. Thus, the diphenyl sulfate sulfate is useful in the glioma-related field and the research field including virus and DNA transfection, and can be used advisably as fluorescence bio-sensor for diagnosing diseases, such as glioma, sarcoma or leukemia.