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1-(8-methoxy-4,4-dimethyl-1-thioxo-1,4-dihydro-5H-[1,2]dithiolo[3,4-c]quinolin-5-yl)-2-phenylethanone is a complex organic compound with a molecular formula of C20H17NO2S3. It is characterized by a 1,2-dithiolo[3,4-c]quinoline core, which features a 1,4-dihydro-5H structure with a 1-thioxo group. The molecule also includes an 8-methoxy group and two methyl groups attached to the 4-position of the quinoline ring. The compound is further defined by a 2-phenylethanone side chain, which is connected to the quinoline core. This chemical structure is likely to be found in specialized applications, such as pharmaceuticals or materials science, due to its unique properties and potential reactivity.

5228-50-2

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5228-50-2 Usage

Molecular structure

The compound has a complex molecular structure consisting of a thioxoquinolin-5-yl group attached to a phenylethanone group.

Potential applications

The compound has potential applications in various fields, including pharmaceuticals, agrochemicals, and materials science, due to its unique structure and functional groups.

Further research

Further research and testing are required to fully understand the compound's potential uses and properties.

Molecular weight

The molecular weight of the compound is approximately 389.52 g/mol.

Appearance

The compound is likely to be a solid, although its exact appearance (e.g., color, crystal structure) is not specified in the provided material.

Solubility

The solubility of the compound in various solvents is not specified in the provided material, but it may vary depending on the polarity of the solvent and the compound's functional groups.

Stability

The stability of the compound under different conditions (e.g., temperature, pH, light exposure) is not specified in the provided material and would require further investigation.

Reactivity

The reactivity of the compound with other chemicals or under specific conditions is not specified in the provided material and would require further study to determine its reactivity profile.

Check Digit Verification of cas no

The CAS Registry Mumber 5228-50-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,2,2 and 8 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 5228-50:
(6*5)+(5*2)+(4*2)+(3*8)+(2*5)+(1*0)=82
82 % 10 = 2
So 5228-50-2 is a valid CAS Registry Number.

5228-50-2Downstream Products

5228-50-2Relevant academic research and scientific papers

Corey-Chaykovsky Cyclopropanation of Nitronaphthalenes: Access to Benzonorcaradienes and Related Systems

Antoniak, Damian,Barbasiewicz, Micha?

supporting information, p. 9320 - 9325 (2019/11/19)

Nitronaphthalene derivatives react as Michael acceptors in the Corey-Chaykovsky reaction with alkyl phenyl selenones and alkyl diphenyl sulfonium salts. Mechanistic studies reveal that sterically demanding substituents at the carbanionic center favor formation of cyclopropanes and suppress competitive β-elimination to the alkylated products. The transformation, demonstrated also on heterocyclic nitroquinoline and nitroindazolines, is an example of transition metal-free dearomatization method.

TRIAZOLO PYRIDINES AS MODULATORS OF GAMMA-SECRETASE

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Page/Page column 15, (2019/07/13)

The present invention relates to triazolo pyridines of formula (II) and their use as modulators of ?-secretase. In particular, the present invention relates to compounds which interfere with ?-secretase and/or its substrate and therefore modulate the form

Discovery of tetrahydroindazoles as a novel class of potent and in vivo efficacious gamma secretase modulators

Gerlach, Kai,Hobson, Scott,Eickmeier, Christian,Gro?, Ulrike,Braun, Clemens,Sieger, Peter,Garneau, Michel,Hoerer, Stefan,Heine, Niklas

, p. 3227 - 3241 (2018/05/23)

The identification and optimization of a novel series of centrally efficacious gamma secretase modulators (GSMs) offering an alternative to the privileged aryl imidazole motif is described. Chiral bicyclic tetrahydroindazolyl amine substituted triazolopyr

An expedient, regioselective synthesis of novel 2-alkylamino- and 2-alkylthiothiazolo[5,4-e]- and -[4,5-g]indazoles and their anticancer potential

Chakrabarty, Manas,Kundu, Taraknath,Arima, Shiho,Harigaya, Yoshihiro

, p. 6711 - 6723 (2008/12/20)

Several novel 2-alkylamino- and 2-alkylthiothiazolo[5,4-e]- and -[4,5-g]indazoles and their 6-alkyl and 8-alkyl derivatives have been synthesised in high overall yields starting from 5-nitro and 6-nitroindazoles in a three-step route involving the regioselective cyclisation of thioureidoindazoles and indazolyl dithiocarbamates as the key steps. Some assorted thiazoloindazoles have been screened for anticancer properties, which demonstrated the anticancer potential of at least one product, justifying its further follow-up.

Efficient and regioselective synthesis of 2-alkyl-2H-indazoles

Cheung, Mui,Boloor, Amogh,Stafford, Jeffrey A.

, p. 4093 - 4095 (2007/10/03)

An efficient and regioselective synthesis of 2-methyl-2H-indazoles and 2-ethyl-2H-indazoles using trimethyloxonium tetrafluoroborate or triethyloxonium hexafluorophosphate is reported.

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