5231-60-7 Usage
Description
An imidazolidinocarbazole alkaloid present in Vinca rosea L., the base is best crystallized from a mixture of C6H6 and light petroleum. It yields colourless
needles and has [α]16D - 31 ° (CHCl3). The ultraviolet spectrum consists of two absorption maxima occurring at 250 and 302 mμ.
References
Moza, Trojanek., Chern. & Ind., 1425 (1962)
Moza, Trojanek., Collect. Czech. Chern. Cornrnun., 28, 1419, 1427 (1963)
Synthesis:
Buchi, Matsumoto, Nishimura.']. A mer. Chern. Soc., 93, 3299 (1971)
Check Digit Verification of cas no
The CAS Registry Mumber 5231-60-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,2,3 and 1 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 5231-60:
(6*5)+(5*2)+(4*3)+(3*1)+(2*6)+(1*0)=67
67 % 10 = 7
So 5231-60-7 is a valid CAS Registry Number.
InChI:InChI=1/C24H30N2O5/c1-5-22-11-8-13-26-14-12-23(18(22)26)16-9-6-7-10-17(16)25(3)19(23)24(29,21(28)30-4)20(22)31-15(2)27/h6-11,18-20,29H,5,12-14H2,1-4H3
5231-60-7Relevant articles and documents
Biomimetic Alkaloid Syntheses. 15. Enantioselective Syntheses with Epichlorohydrin: Total Syntheses of (+)-, (-)-, and (+/-)-Vindoline and a Synthesis of (-)-Vindorosine
Kuehne, Martin E.,Podhorez, David E.,Mulamba, Tshilundu,Bornmann, William G.
, p. 347 - 353 (2007/10/02)
Total syntheses of vindoline (1) in racemic as well as in each enantiomeric form and of (-)-vindorosine (2) are described.They were achieved by generation and diastereoselective cyclizations of 14-hydroxysecodine intermediates 6 and 7.The subsequent oxidative elaboration of ring E was also studied with 3-oxotabersonine (24), 3-oxovincadifformine (26), and 14β-hydroxyvincadifformine (15).Na-Methyltabersonine (22) was oxidized to a ring-D-contracted α-keto lactam, 23.
The total synthesis of (plus or minus)-vindorosine.
Buechi,Matsumoto,Nishimura
, p. 3299 - 3301 (2007/10/04)
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