52355-51-8

Basic information

• Product Name: diethyl 10-undecenylmalonate
• Synonyms: diethyl 10-undecenylmalonate
• CAS NO: 52355-51-8
• Molecular Weight: 312.45
• Mol File: 52355-51-8.mol

Chemical Properties

• CAS DataBase Reference: diethyl 10-undecenylmalonate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl 10-undecenylmalonate(52355-51-8)
• EPA Substance Registry System: diethyl 10-undecenylmalonate(52355-51-8)

Safety Data

• Hazardous Substances Data: 52355-51-8(Hazardous Substances Data)

Upstream product

• 7766-50-9 1-undecen-11-ylbromide 
• 105-53-3 diethyl malonate 

Downstream Products

• 6006-06-0 12-tridecenoic acid 
• 4475-28-9 undec-10-enyl-malonic acid 

Relevant articles and documents

Total Synthesis of Laucysteinamide A, a Monomeric Congener of Somocystinamide A

Laucysteinamide A (4) is a marine natural product isolated from the cyanobacterium Caldora penicillata and contains structural motifs found in promising cancer drug leads. The first total synthesis of 4 and its analogues was achieved, which also enabled a concise formal synthesis of somocystinamide A (3), a dimeric congener of 4 that previously showed extremely potent antiproliferative activities. This work provides further insights on structure-activity relationships in this class of natural products.

AVOIDANCE OF NON-SPECIFIC BINDING ON AN ACOUSTIC WAVE BIOSENSOR USING LINKER AND DILUENT MOLECULES FOR DEVICE SURFACE MODIFICATION

An acoustic wave biosensor comprising a surface of a mixed self-assembling monolayer for receiving a probe-biomolecule is described herein. The biosensor surface may comprise a piezoelectric quartz crystal,—for detection purposes with the electromagnetic piezoelectric acoustic sensor (EMPAS)—upon which a mixed self-assembling monolayer is formed, which includes at least one linker, such as 2,2,2-trifluoroethyl-13-trichlorosilyl-tridecanoate (TTTA); its oligoethylene glycol (OEG) analog OEGylated TTTA (OEG-TTTA); S-(2-(2-(2-(3-trichlorosilyl-propyloxy)-ethoxy)-ethoxy)-ethyl)-benzenethiosulfonate (OEG-TU BTS). Linker/diluent systems for attaching a functionalizing entity to the surface of a biosensor are described, as well as methods for preparing a biosensor surface with an oligoethylene glycol linker.

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