52372-91-5Relevant academic research and scientific papers
An Alternative Metal-Free Aerobic Oxidative Cross-Dehydrogenative Coupling of Sulfonyl Hydrazides with Secondary Phosphine Oxides
Cheng, Feixiang,Liu, Jianjun,Liu, Teng,Yu, Rong,Zhang, Yanqiong
, p. 253 - 262 (2019/12/28)
An alternative metal-free, efficient and practical approach for the preparation of phosphinothioates is established via the aerobic oxidative cross-dehydrogenative coupling (CDC) of sulfonyl hydrazides with secondary phosphine oxides catalyzed by tetrabutylammonium iodide (TBAI) in the presence of atmospheric oxygen. The strategy provides an array of diverse phosphinothioates in good to excellent yields. Furthermore, two representative bioactive molecules are synthesized on up to gram scale by utilizing this method.
Solvent-free preparation method of alkylthiophosphonate
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Paragraph 0036-0042, (2019/03/06)
The invention discloses a solvent-free preparation method of an alkylthiophosphonate. The method comprises the following steps: 1) mixing an alcohol compound, a sulfur powder and a pH reagent, and reacting under the action of Bronsted acid at a temperatur
Metal- and oxidant-free S-P(O) bond construction: Via direct coupling of P(O)H with sulfinic acids
Moon, Youngtaek,Moon, Yonghoon,Choi, Hangyeol,Hong, Sungwoo
, p. 1005 - 1013 (2017/08/14)
We have developed a simple and convenient method for S-P(O) bond formation between R2P(O)H and sulfinic acids under metal-, oxidant-, and halogen-free conditions. The current method is compatible with a broad range of substituents on various substrates including halogens and heterocyclic moieties. The synthetic potential of this method was further highlighted by the expeditious synthesis of optically active P-chiral phosphorothioates via stereospecific coupling.
TBPB-promoted metal-free synthesis of thiophosphinate/phosphonothioate by direct P-S bond coupling
Wang, Jichao,Huang, Xin,Ni, Zhangqin,Wang, Sichang,Wu, Jun,Pan, Yuanjiang
, p. 314 - 319 (2018/04/16)
An efficient method for the direct coupling of thiol/thiophenol with H-phosphine oxides or H-phosphinate esters is reported. Without using any metallic catalyst, the direct sulfur-phosphorus bond coupling reaction was promoted using tert-butyl peroxybenzo
A NEW, UNEXPECTED REACTION OF PHOSPHONOCHLORIDOTHIONATES WITH ALKYL ARYL ETHERS AND ALKYL CHLORIDES UNDER THE FRIEDEL-CRAFTS REACTION CONDITIONS
Omelanczuk, Jan
, p. 93 - 102 (2007/10/02)
Phosphonochloridothionates have been found to react in the presence of Lewis acids with alkyl aryl ethers to give S-alkyl O-aryl phosphonothiolates and with alkyl halides to form products of the S-alkylation. Key words: Alkyl arel ethers; phosphonochloridothionates; alkylation; S-alkyl O-aryl phosphonothiolates; S-alkyl alkyl(aryl) dichlorophosphonium salts; conductivity.
