52373-02-1

Usage

Uses

1,2,3,4-Tetrahydro-6-methoxy-1-naphthalenamine is used as a chemical intermediate in the synthesis of various organic compounds and pharmaceuticals. Its specific applications may vary depending on the industry and the desired end product.
Used in Pharmaceutical Industry:
1,2,3,4-Tetrahydro-6-methoxy-1-naphthalenamine is used as a building block for the development of new drugs, potentially contributing to the creation of novel therapeutic agents.
Used in Chemical Synthesis:
1,2,3,4-Tetrahydro-6-methoxy-1-naphthalenamine is used as a reagent in the synthesis of complex organic molecules, which may have applications in various fields such as materials science, agrochemicals, and specialty chemicals.

InChI:InChI=1/C11H15NO/c1-13-9-5-6-10-8(7-9)3-2-4-11(10)12/h5-7,11H,2-4,12H2,1H3

Upstream product

• 120342-64-5 1-azido-6-methoxy-1,2,3,4-tetrahydronaphthalene 
• 1078-19-9 6-methoxy-3,4-dihydro-1(2H)-naphthalenone 
• 16821-32-2 6-methoxy-1,2,3,4-tetrahydronaphthalen-1-ol 
• 1730-48-9 6-methoxy-1,2,3,4-tetrahydronaphthalene 
• 536717-83-6 O-tert-butyldimethylsilyl-6-methoxy-1-tetralone oxime 

Downstream Products

• 39226-88-5 6-methoxy-1,2,3,4-tetrahydronaphthalene-1-ylamine hydrochloride 
• 314019-11-9 (S)-6-methoxy-1,2,3,4-tetrahydro-1-naphthylamine 

Relevant academic research and scientific papers

PERIPHERAL ALKYL AND ALKENYL CHAINS EXTENDED BENZENE DERIVATIVES AND PHARMACEUTICAL COMPOSITION INCLUDING THE SAME

The compounds represented by Formula (I), which are peripheral alkyl and alkenyl chains extended benzene derivatives, are useful as dual autotaxin (ATX) / histone deacetylase (HD AC) inhibitors. These compounds may be included in a pharmaceutical composition along with a pharmaceutically acceptable carrier, and be used in a therapeutically effective amount for prophylaxis or treatment of various diseases and disorders.

SUBSTITUTED ARYLAMINE COMPOUNDS AND THEIR USE AS 5-HT6 MODULATORS

The invention relates to 5-HT6 receptor antagonists. Novel arylamine compounds having the formula: (see formula I) and pharmaceutically acceptable salts and/or esters thereof, wherein - n is 0, 1, 2, 3, or 4; - A, when present is a lower alkyl

Facile rearrangement of O-silylated oximes on reduction with boron trifluoride/borane

Aromatic O-triisopropylsilyl ketoximes were efficiently rearranged to cyclic and acyclic aniline derivatives on reduction with BF3- ethearate /borane. The bulk of the substituents on the silicon atom, the size of the aliphatic ring, and the presence of alkoxy substituents on the aryl group all play an important role in the aniline.

Substituted aryl 1,4-pyrazine derivatives

Substituted aryl 1,4-pyrazine derivatives and their use in treating anxiety disorders, depression and stress related disorders are disclosed.

Selective Conversion of Benzylic C-H Bonds to an Amine Function by Oxidative Nucleophilic Substitution

The benzylic proton of alkylarenes 1 was replaced by an azido group in one step by reaction with trimethylsilyl azide or hydrazoic acid in chloroform in the presence of 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ).The 1-arylalkyl azides 2 were reduced to amines 3, which were characterized as their hydrochlorides 4.