52378-63-9

Basic information

• Product Name: (3-AMINO-PYRIDIN-2-YL)-METHANOL
• Synonyms: 3-aMino-2-PyridineMethanol;2-Pyridinemethanol, 3-amino-;3-AMINO-2-(HYDROXYMETHYL)PYRIDINE;(3-AMINO-PYRIDIN-2-YL)-METHANOL;3-Aminopyridine-2-methanol
• CAS NO: 52378-63-9
• Molecular Formula: C₆H₈N₂O
• Molecular Weight: 124.14
• Product Categories: pharmacetical
• Mol File: 52378-63-9.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 333.1 °C at 760 mmHg
• Flash Point: 155.3 °C
• Appearance: /
• Density: 1.257 g/cm³
• Vapor Pressure: 5.53E-05mmHg at 25°C
• Refractive Index: 1.627
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 13.34±0.10(Predicted)
• CAS DataBase Reference: (3-AMINO-PYRIDIN-2-YL)-METHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: (3-AMINO-PYRIDIN-2-YL)-METHANOL(52378-63-9)
• EPA Substance Registry System: (3-AMINO-PYRIDIN-2-YL)-METHANOL(52378-63-9)

Safety Data

• Hazardous Substances Data: 52378-63-9(Hazardous Substances Data)

Usage

General Description

"(3-Amino-pyridin-2-yl)-methanol is a complex organic compound that belongs to the class of chemical compounds known as aminomethylpyridines. It is composed of an amino pyridine ring, which is a derivative of pyridine (a six-membered ring with five carbon atoms and one nitrogen atom) with an amino group attached, and a methanol group. This chemical complex is mainly used in various aspects of scientific research and development, primarily for the synthesis of other types of compounds. Its specific chemical formula is C6H8N2O, and it has a molar mass of 124.14 g/mol. As with many organic chemical compounds, handling "(3-Amino-pyridin-2-yl)-methanol" requires appropriate safety measures due to its potential reactivity.

InChI:InChI=1/C6H8N2O/c7-5-2-1-3-8-6(5)4-9/h1-3,9H,4,7H2

Upstream product

• 36052-27-4 methyl 3-aminopicolinate 
• 1462-86-8 3-amino-pyridine-2-carboxylic acid 
• 824429-51-8 N-[2-(hydroxymethyl)pyridin-3-yl]carbamic acid tert-butyl ester 
• 27507-15-9 ethyl 3-aminopyridine-2-carboxylate 

Downstream Products

• 1350294-36-8 N-(2-hydroxymethyl-pyridin-3-yl)-benzamide 
• 55234-58-7 3-aminopyridine-2-carboxaldehyde 
• 894792-12-2 1-(2-(methylmercapto)-pyrimidin-4-yl)-7-phenyl-1,2,3,4-tetrahydro-1,8-naphthyridine 
• 60588-81-0 3-chloro-2-hydroxy-methyl-pyridine 
• 1285514-30-8 N-[2-(hydroxymethyl)-3-pyridinyl]-2-[(phenylmethyl)oxy]-5-(4-pyridinyl)benzamide 
• 894791-94-7 7-phenyl-1,2,3,4-tetrahydro-1,5-naphthyridine 
• 791856-65-0 6-phenyl-1,2,3,4-tetrahydro-1,5-naphthyridine 

Relevant articles and documents

Synthesis of some benzo[b][1,8] and [1,5]naphthyridines

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NOVEL COMPOUNDS

The present invention discloses novel compounds inhibiting LRRK2 kinase activity, the preparation processes thereof, the compositions containing them, as well as the use in treating diseases characterized by LRRK2 kinase activity, particularly Parkinson's disease and Alzheimer's disease.

UV photoelectron spectroscopy studies of the diazaxylylenes generated from amino(hydroxymethyl)pyridines

Diazaxylylenes generated by 1,4-elimination of water from amino(hydroxymethyl)pyridines under flash vacuum thermolysis (FVT) conditions can be directly studied by the UV-photoelectron spectroscopy (UV-PES). The elimination of water from these compounds starts at 450°C and is completed at 500-550°C. The interpretation of UV-photoelectron spectra was supported by Density Functional Theory studies.