894792-12-2Relevant academic research and scientific papers
A 1, 2, 3, 4-tetrahydronaphthalene [...] compound synthesis method and application
-
Paragraph 0108; 0109, (2018/02/04)
The invention belongs to the technical field of pharmaceutical chemical synthesis and in particular relates to a synthesis method and application of a 1,2,3,4-tetrahydronaphthyridine compound. The synthesis method of the 1,2,3,4-tetrahydronaphthyridine co
Ruthenium-Catalyzed Straightforward Synthesis of 1,2,3,4-Tetrahydronaphthyridines via Selective Transfer Hydrogenation of Pyridyl Ring with Alcohols
Xiong, Biao,Li, Ya,Lv, Wan,Tan, Zhenda,Jiang, Huanfeng,Zhang, Min
, p. 4054 - 4057 (2015/09/01)
Through a ruthenium-catalyzed selective hydrogen transfer coupling reaction, a novel straightforward synthesis of 1,2,3,4-tetrahydronaphthyridines from o-aminopyridyl methanols and alcohols has been developed. The synthetic protocol proceeds in an atom- a
SUBSTITUTED HETEROCYCLIC COMPOUNDS AND METHODS OF USE
-
Page/Page column 54, (2008/06/13)
The present invention relates to nitrogen-containing compounds according to formula (I) and pharmaceutically acceptable salts thereof. Also included is a method of treatment of inflammation, rheumatoid arthritis, Pagets disease, osteoporosis, multiple myeloma, uveititis, acute or chronic myelogenous leukemia, pancreatic ? cell destruction, osteoarthritis, rheumatoid spondylitis, gouty arthritis, inflammatory bowel disease, adult respiratory distress syndrome (ARDS), psoriasis, Crohn's disease, allergic rhinitis, ulcerative colitis, anaphylaxis, contact dermatitis, asthma, muscle degeneration, cachexia, Reiter's syndrome, type I diabetes, type II diabetes, bone resorption diseases, graft vs. host reaction, Alzheimer's disease, stroke, myocardial infarction, ischemia reperfusion injury, atherosclerosis, brain trauma, multiple sclerosis, cerebral malaria, sepsis, septic shock, toxic shock syndrome, fever, myalgias due to HIV-1, HIV-2, HIV-3, cytomegalovirus (CMV), influenza, adenovirus, the herpes viruses or herpes zoster infection in a mammal comprising administering an effective amount a compound as described above.
