5238-36-8Relevant articles and documents
SYNTHETIC RETINOIDS FOR USE IN RAR ACTIVATION
-
, (2020/09/27)
The present invention relates to compounds of formula I: in which A1-A7 and R1 to R5 are defined herein, for use in the treatment of a condition or disease which is alleviated by the activation of retinoic acid receptors (RAR). The invention also relates to pharmaceutical compounds comprising such compounds, and related methods of treatment. In an aspect, the invention relates to a method of screening compounds for therapeutic potential in the treatment of a condition or disease which is alleviated by the activation of retinoic acid receptors (RAR). Aspects of the invention relate to novel compounds of formula I in which at least one of A1 to A3 is N or at least one of A4 is CR12 or A5 is CR13 in which R12/R13 is halogen.
SYNTHESIS OF LIGANDS FOR USE IN ACTINIDE EXTRACTION
-
Page/Page column 19-20, (2011/07/09)
The invention discloses an improved process for the preparation of 2,2,5,5-tetrasubstituted hexane-1,6-dicarbonyl compounds, and in particular diethyl 2,2,5,5-tetramethylhexanedioate and dimethyl 2,2,5,5-tetramethylhexanedioate, by the alkylation of 1,2-d
Interaction of 6,6′′-bis(5,5,8,8-tetramethyl-5,6,7,8- tetrahydro-1,2,4-benzotriazin-3-yl)-2,2′:6′,2′′- terpyridine (CyMe4-BTTP) with some trivalent ions such as lanthanide(iii) ions and americium(iii)
Lewis, Frank W.,Harwood, Laurence M.,Hudson, Michael J.,Drew, Michael G. B.,Modolo, Giuseppe,Sypula, Michal,Desreux, Jean F.,Bouslimani, Nouri,Vidick, Geoffrey
experimental part, p. 5172 - 5182 (2010/07/08)
The new ligand 6,6′′-bis(5,5,8,8-tetramethyl-5,6,7,8- tetrahydro-1,2,4-benzotriazin-3-yl)-2,2′:6′,2′′- terpyridine (CyMe4-BTTP) has been synthesized in 4 steps from 2,2′:6′,2′′-terpyridine. Detailed NMR and mass spectrometry studies indicate th
