52448-15-4 Usage
General Description
The chemical compound (S)-2-amino-3-(5-chloro-1H-indol-3-yl)-propionic acid, also known as 5-Cl-Tryptophan, is an amino acid derivative that contains a 5-chloroindole group. It is a chiral compound, with the (S)-enantiomer being the biologically active form. (S)-2-amino-3-(5-chloro-1H-indol-3-yl)-propionic acid is commonly used as a building block in the synthesis of peptide-based drugs and pharmaceuticals. It may also have potential applications in the fields of neuroscience and medicinal chemistry due to its ability to modulate specific receptors and enzymes in the central nervous system. Furthermore, it is being investigated for its potential use in the treatment of neurodegenerative diseases and mood disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 52448-15-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,4,4 and 8 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 52448-15:
(7*5)+(6*2)+(5*4)+(4*4)+(3*8)+(2*1)+(1*5)=114
114 % 10 = 4
So 52448-15-4 is a valid CAS Registry Number.
52448-15-4Relevant articles and documents
Syntheses of Substituted L- and D-Tryptophans
Irie, Kunihiko,Ishida, Akihiko,Nakamura, Tohru,Oh-ishi, Tokuro
, p. 2126 - 2139 (2007/10/02)
Several 5-substituted nb-methoxycarbonyl-L- and -D-tryptophan derivatives were synthesized from proline by a new route involving electrochemical oxidation, as well as by the known procedures.Removal of the Nb-methoxycarbonyl group was accomplished by treatment with Me3SiI in refluxing chloroform, then alkaline hydrolysis of the methyl esters afforded 5-substituted L- and D-tryptophans with high optical purities.Keywords - L-tryptophan 5-substituted; D-tryptophan 5-substituted; anodic oxidation; N-methoxycarbonyl group deprotection; Fischer indole synthesis; iodotrimethylsilane
