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(S)-2-AMINO-3-(5-CHLORO-1H-INDOL-3-YL)-PROPIONIC ACID, also known as 5-Cl-Tryptophan, is a chiral amino acid derivative featuring a 5-chloroindole group. As the biologically active (S)-enantiomer, it serves as a crucial building block in the synthesis of peptide-based drugs and pharmaceuticals. Its unique structure allows it to modulate specific receptors and enzymes within the central nervous system, making it a promising candidate for research and development in neuroscience and medicinal chemistry. Additionally, it is under investigation for its potential therapeutic effects in treating neurodegenerative diseases and mood disorders.

52448-15-4

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52448-15-4 Usage

Uses

Used in Pharmaceutical Synthesis:
(S)-2-AMINO-3-(5-CHLORO-1H-INDOL-3-YL)-PROPIONIC ACID is used as a key building block for the synthesis of peptide-based drugs and pharmaceuticals, leveraging its ability to modulate specific receptors and enzymes in the central nervous system.
Used in Neuroscience Research:
In the field of neuroscience, (S)-2-AMINO-3-(5-CHLORO-1H-INDOL-3-YL)-PROPIONIC ACID is utilized as a research compound to explore its interactions with the central nervous system, potentially leading to advancements in understanding and treating neurological conditions.
Used in Medicinal Chemistry:
(S)-2-AMINO-3-(5-CHLORO-1H-INDOL-3-YL)-PROPIONIC ACID is employed as a chiral compound in medicinal chemistry for the development of new therapeutic agents targeting the central nervous system, given its potential to modulate specific receptors and enzymes.
Used in Neurodegenerative Disease Treatment:
In the medical field, (S)-2-AMINO-3-(5-CHLORO-1H-INDOL-3-YL)-PROPIONIC ACID is being investigated for its potential use in the treatment of neurodegenerative diseases, due to its ability to modulate relevant biological targets and pathways.
Used in Mood Disorder Treatment:
(S)-2-AMINO-3-(5-CHLORO-1H-INDOL-3-YL)-PROPIONIC ACID is also being explored for its potential therapeutic effects in mood disorders, as its modulation of central nervous system receptors and enzymes may contribute to the management of such conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 52448-15-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,4,4 and 8 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 52448-15:
(7*5)+(6*2)+(5*4)+(4*4)+(3*8)+(2*1)+(1*5)=114
114 % 10 = 4
So 52448-15-4 is a valid CAS Registry Number.

52448-15-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name (S)-2-AMINO-3-(5-CHLORO-1H-INDOL-3-YL)-PROPIONIC ACID

1.2 Other means of identification

Product number -
Other names 5-CHLORO-L-TRYPTOPHAN

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:52448-15-4 SDS

52448-15-4Downstream Products

52448-15-4Relevant academic research and scientific papers

Syntheses of Substituted L- and D-Tryptophans

Irie, Kunihiko,Ishida, Akihiko,Nakamura, Tohru,Oh-ishi, Tokuro

, p. 2126 - 2139 (2007/10/02)

Several 5-substituted nb-methoxycarbonyl-L- and -D-tryptophan derivatives were synthesized from proline by a new route involving electrochemical oxidation, as well as by the known procedures.Removal of the Nb-methoxycarbonyl group was accomplished by treatment with Me3SiI in refluxing chloroform, then alkaline hydrolysis of the methyl esters afforded 5-substituted L- and D-tryptophans with high optical purities.Keywords - L-tryptophan 5-substituted; D-tryptophan 5-substituted; anodic oxidation; N-methoxycarbonyl group deprotection; Fischer indole synthesis; iodotrimethylsilane

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