524729-72-4

Basic information

• Product Name: 3-Isoxazolecarboxylicacid,4,5-dihydro-5-methyl-,methylester(9CI)
• Synonyms: 3-Isoxazolecarboxylicacid,4,5-dihydro-5-methyl-,methylester(9CI)
• CAS NO: 524729-72-4
• Molecular Formula: C6H9NO3
• Molecular Weight: 143.14
• Product Categories: CARBOXYLICESTER
• Mol File: 524729-72-4.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Isoxazolecarboxylicacid,4,5-dihydro-5-methyl-,methylester(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Isoxazolecarboxylicacid,4,5-dihydro-5-methyl-,methylester(9CI)(524729-72-4)
• EPA Substance Registry System: 3-Isoxazolecarboxylicacid,4,5-dihydro-5-methyl-,methylester(9CI)(524729-72-4)

Safety Data

• Hazardous Substances Data: 524729-72-4(Hazardous Substances Data)

Usage

Structure

Contains an isoxazole ring structure and a carboxylic acid functional group

Physical State

Yellow liquid at room temperature

Stability

Stable under normal conditions

Common Uses

Intermediate in pharmaceutical and agrochemical synthesis; potential applications in organic synthesis and chemical research

Handling

Requires careful handling and storage in accordance with safety regulations and guidelines due to potential hazards and risks

Upstream product

• 187737-37-7 propene 
• 30673-27-9 methyl chlorooximidoacetate 

Relevant articles and documents

New N-aryl isoxazolecarboxamides and N-isoxazolylbenzamides as anticonvulsant agents

We prepared a series of N-aryl isoxazolecarboxamide, N-isoxazolylbenzamide compounds and derivatives and studied their anticonvulsant action in MES and MMS tests. Some of these reveal considerable activity, especially with respect to MES test. The disubstitution in the 2.6-position on the phenyl ring by two methyl groups would appear to be of primary importance for the activity. The amide bridge between the phenyl and isoxazolic rings, whether of the anilide or benzamide type, seems to show similar anticonvulsant behavior. We have selected the derivatives 8 (N-(2.6-dimethylphenyl)-5-methyl-3-isoxazolecarboxamide, 12 (N-(2.6-dimethylphenyl)-5-hydroxymethyl-3-isoxazolecarboxamide) and 51 (N-(5-methyl-3-isoxazolyl)-2.6-dimethylbenzamide) which are presently being studied in more extended pharmacological tests.