524735-85-1Relevant articles and documents
New ligands for asymmetric diethylzinc additions to aromatic aldehydes, demonstrating substrate-dependent nonlinear effects
Bulman Page, Philip C.,Allin, Steven M.,Maddocks, Suzanne J.,Elsegood, Mark R.J.
, p. 2827 - 2832 (2002)
The development of aziridine-based ligands for the asymmetric addition of diethylzinc to a selection of aromatic aldehydes was discussed. One zinc atom was chelated by the aminoalcohol ligand and associated with the aldehyde oxygen atom. The x-ray analysi
Novel polymer-bound aminoalcohol ligands for the asymmetric addition of diethylzinc to aldehydes
Page, Philip C. Bulman,Allin, Steven M.,Dilly, Suzanne J.,Buckley, Benjamin R.
, p. 2019 - 2030 (2008/02/05)
The synthesis of several novel polymer-supported aziridine-containing aminoalcohol chiral ligands has been accomplished, and the polymers have been used as ligands for the catalytic asymmetric addition of diethylzinc to benzaldehyde, giving up to 89% ee. Incorporation onto a polymer support prevents the variation of ee with time that is observed in reactions of one unsupported ligand, perhaps as a result of site isolation of the ligand within the polymer, preventing cooperative effects. Copyright Taylor & Francis Group, LLC.
