5248-51-1Relevant academic research and scientific papers
Trizaine-based dehydrative condensation reagents bearing carbon-substituents
Kitamura, Masanori,Komine, Sayaka,Kunishima, Munetaka,Yamada, Kohei
, (2020/02/22)
Herein, we report on the synthesis of alkyl-, aryl-, and alkynyl-substituted chlorotriazines and their ammonium salts, and demonstrate their utility in dehydrative condensation reactions. Although the electrophilicity of these reagents is mainly dependent on the hybridization of the carbon-substituents, it was found that bulky 2,6-dimethylphenyl group-substituted reagents resulted in the highest product yields because of a slight increase in reagent electrophilicity and/or steric hindrance favorable for desired dehydrative condensation reactions.
