52483-91-7Relevant articles and documents
Novel fluorescent probes for singlet oxygen
Umezawa, Naoki,Tanaka, Kumi,Urano, Yasuteru,Kikuchi, Kazuya,Higuchi, Tsunehiko,Nagano, Tetsuo
, p. 2899 - 2901 (1999)
The first fluorescent chemical traps for 1O2 have been developed. DPAXs react specifically with 1O2 to yield the corresponding endoperoxides, DPAX-EPs (see scheme; X = H, Cl, F). DPAXs scarcely fluoresce, while DPAX-EPs are strongly fluorescent. Since the fluorescence of these probes is unaffected by H2O2, superoxide, and nitric oxide, they are useful for the selective detection of 1O2 in biological systems.