52494-32-3 Usage
Uses
Used in Pharmaceutical Industry:
5-M-Tolylamino-[1,3,4]thiadiazole-2-thiol is used as a potential therapeutic agent for its antimicrobial properties, offering a new avenue for combating resistant bacteria and other microorganisms.
5-M-Tolylamino-[1,3,4]thiadiazole-2-thiol is used as a potential anticancer agent, leveraging its ability to target and inhibit the growth of cancer cells, providing a novel approach to cancer treatment.
5-M-Tolylamino-[1,3,4]thiadiazole-2-thiol is used as an anti-inflammatory agent, due to its capacity to reduce inflammation and alleviate symptoms associated with various inflammatory conditions.
The diverse biological activities of 5-M-Tolylamino-[1,3,4]thiadiazole-2-thiol, combined with its unique molecular structure, position it as an interesting target for further research and development in the pharmaceutical industry, with the potential to contribute to the advancement of new treatments for various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 52494-32-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,4,9 and 4 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 52494-32:
(7*5)+(6*2)+(5*4)+(4*9)+(3*4)+(2*3)+(1*2)=123
123 % 10 = 3
So 52494-32-3 is a valid CAS Registry Number.
InChI:InChI=1/C9H9N3S2/c1-6-3-2-4-7(5-6)10-8-11-12-9(13)14-8/h2-5H,1H3,(H,10,11)(H,12,13)
52494-32-3Relevant academic research and scientific papers
Synthesis and antifungal activities of ω-(5-arylamino-1,3,4-thiadiazol-2-thio)-ω(1H-1,2,4-triazol-1-yl) acetophenones
Chu, Chang-Hu,Hui, Xin-Ping,Xu, Peng-Fei,Zhang, Zi-Yi,Li, Zhi-Chun,Liao, Ren-An
, p. 2436 - 2438 (2007/10/03)
Several ω-(5-arylamino-1,3,4-thiadiazol-2-thiol)-ω-(1H-1,2,4-triazol-1- yl)acetophenones 4a-i have been synthesized. The representative compounds exhibit some antifungal and plant growth regulatory activities. The structures of these compounds have been confirmed by elemental analyses, 1H NMR, IR and MS spectra.
an interesting isomerization: synthesis of mesoionic 5-arylamino-1,3,4-thiadiazolium-2-thiolates by using ω-bromo-ω-(1H-1,2,4-triazol-1-yl)acetophenone as catalyst
Chu, Chang-Hu,Hui, Xin-Ping,Xu, Peng-Fei,Zhang, Zi-Yi,Li, Zhi-Chun,Liao, Ren-An
, p. 943 - 946 (2007/10/03)
Mesoionic 5-arylamino-1,3,4-thiadiazolium-2-thiolates 7a-f were prepared by the isomerization of 5-arylamino-1,3,4-thiadiazol-2-thiones 5a-f by using ω-bromo-ω-(1H-1,2,4-triazol-1-yl)acetophenone 6 as catalyst. All the structures of mesoionic synthesized were confirmed by elemental analyses, 1H NMR, IR and MS spectral data. We have also determined the x-ray photoelectron spectroscopy (XPS) of the mesoionic and their precursors. A comparison of XPS spectra between the mesoionic and their precursors showed that the charge separation in mesoionic is distinctly larger than in their precursors.