52497-08-2

Basic information

• Product Name: 1-chloro-3-phenylbut-1-ene
• Synonyms: 1-chloro-3-phenylbut-1-ene
• CAS NO: 52497-08-2
• Molecular Weight: 166.65
• Mol File: 52497-08-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-chloro-3-phenylbut-1-ene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-chloro-3-phenylbut-1-ene(52497-08-2)
• EPA Substance Registry System: 1-chloro-3-phenylbut-1-ene(52497-08-2)

Safety Data

• Hazardous Substances Data: 52497-08-2(Hazardous Substances Data)

Upstream product

• 156-60-5 trans-1,2-dichloroethylene 
• 100-41-4 ethylbenzene 
• 34713-70-7 2-Phenylpropanal 
• 247943-55-1 1-chloro-1-iodo-3-phenylbut-2-yl acetate 

Relevant articles and documents

Synthesis of (E)-α,β-unsaturated esters and (Z)-vinyl halides with total or high diastereoselectivity by using samarium metal

A highly diastereoselective β-elimination of 2-halo-3-hydroxy esters 1 or O-acetylated 1,1-dihaloalkan-2-ols 4 is achieved with samarium in the presence of diiodomethane, yielding α,β-unsaturated esters 2 or vinyl halides 5, respectively. The β-elimination reaction was promoted by samarium diiodide, which was generated in situ. The starting halohydrins 1 or 4 are easily prepared by reaction of the corresponding lithium enolates of α-halo esters or dihalomethyllithium with aldehydes at -78°C. The influence of the reaction conditions and the structure of the starting compounds on the diastereoselectivity of the β-elimination reactions is discussed, A comparative study of the β-elimination reaction with preformed SmI2 and metallic samarium is also performed. These elimination reactions can be explained by the proposed mechanism. Wiley-VCH Verlag GmbH, 69451 Weinheim, Germany, 2002).