525-68-8

Usage

Uses

Used in Pharmaceutical Industry:
Galipine is used as a potential therapeutic agent for the treatment of diseases involving acetylcholine imbalances, such as Alzheimer's disease, due to its ability to inhibit the enzyme acetylcholinesterase.
Used in Neurological Applications:
Galipine is used as a neuroprotective agent to maintain the balance of acetylcholine, a neurotransmitter, in the brain, potentially improving cognitive function and slowing the progression of neurodegenerative diseases.
Used in Research and Development:
Galipine is used as a subject of study in pharmacological research to further understand its effects on acetylcholinesterase inhibition and explore its potential therapeutic applications in various diseases and conditions.

InChI:InChI=1/C20H21NO3/c1-22-18-11-9-14(12-20(18)24-3)8-10-15-13-19(23-2)16-6-4-5-7-17(16)21-15/h4-7,9,11-13H,8,10H2,1-3H3

Upstream product

• 199279-19-1 dehydrogalipin 
• 186581-53-3 diazomethane 
• 199279-10-2 1-(3,4-dimethoxyphenyl)-5-(2-nitrophenyl)pentane-1,3,5-trione 
• 199279-12-4 1-(2-aminophenyl)-5-(3,4-dimethoxyphenyl)pentane-1,3,5-trione 
• 199279-13-5 2-<2-(3,4-dimethoxyphenyl)-2-oxoethyl>quinolin-4-one 
• 199279-11-3 2-(3,4-dimethoxyphenyl)-6-(2-nitrophenyl)-4H-pyran-4-one 
• 199279-14-6 2-(2-aminophenyl)-6-(3,4-dimethoxyphenyl)-4H-pyran-4-one 
• 179243-01-7 5-(2-Nitro-phenyl)-furan-2,3-dione 
• 79631-01-9 1,2-dimethoxy-4-<1-<(1,1-dimethylethyl)dimethylsilyloxy>ethenyl>benzene 

Downstream Products

• 93-07-2 Veratric acid 
• 99-50-3 3,4-Dihydroxybenzoic acid 

Relevant academic research and scientific papers

Synthesis of 2-aroylmethylquinolin-4-ones via the addition reaction of ortho-nitrobenzoylketene to 1-aryl-l-trimethylsilyloxyethylenes

Catalytic hydrogenation of 1-aryl-5-(2-nitrophenyl)pentane-1,3,5-triones A over 10% Pd-C caused selective reduction of the nitro group with concomitant cyclization to give 2-aroylmethylquinolin-4-ones B. This provides a simple method of quinolin-4-one synthesis.