52550-98-8

Upstream product

• 75-15-0 carbon disulfide 
• 615-36-1 2-bromoaniline 
• 13037-60-0 1-bromo-2-isothiocyanatobenzene 

Downstream Products

• 725-42-8 bis-(2-bromo-phenyl)-carbodiimide 
• 73219-56-4 3-(2-bromo-phenyl)-thiazolidine-2,4-dione 
• 52476-94-5 3-(2-bromo-phenyl)-2-(2-bromo-phenylimino)-thiazolidin-4-one 
• 859775-07-8 N-anilino-N',N''-bis-(2-bromo-phenyl)-guanidine 

Relevant academic research and scientific papers

Thiourea type nitrogen phosphine ligand and preparation method and application thereof

The invention provides a thiourea type nitrogen phosphine ligand and a preparation method and application thereof. The thiourea-type nitrogen phosphine ligand is reacted with aromatic amine and aryl isothiocyanate to obtain aryl thiourea, and then reacted

Novel non-peptidic small molecule inhibitors of secreted aspartic protease 2 (SAP2) for the treatment of resistant fungal infections

Targeting secreted aspartic protease 2 (SAP2), a kind of virulence factor, represents a new strategy for antifungal drug discovery. In this report, the first-generation of small molecule SAP2 inhibitors was rationally designed and optimized using a structure-based approach. In particular, inhibitor 23h was highly potent and selective and showed good antifungal potency for the treatment of resistant Candida albicans infections.