525575-18-2Relevant academic research and scientific papers
Synthesis of N-Fmoc 3-(4-(di-(tert-butyl)phosphonomethyl)-phenyl)pipecolic acid as a conformationally constrained phosphotyrosyl mimetic suitably protected for peptide synthesis
Liu, Ding-Guo,Wang, Xiang-Zhu,Gao, Yang,Li, Bihua,Yang, Dajun,Burke Jr., Terrence R.
, p. 10423 - 10428 (2007/10/03)
Phosphonomethylphenylalanine (Pmp, 2) has shown wide utility as a hydrolytically stable phosphtyrosyl (pTyr, 1) mimetic, particularly in Src homology 2 (SH2) domain-binding peptides. (2S,3R)-3-(4-(phosphonomethyl)phenyl)pipecolic acid (3) represents a var
