525575-19-3

Upstream product

• 39061-59-1 t-butoxalyl chloride 
• 510773-83-8 methyl (2S,3R)-3-(4-((bis-(tert-butyl)phosphono)methyl)phenyl)piperidine-2-carboxylate 
• 510773-80-5 (4S)-3-((3S)-3-(4-((bis-(tert-butyl)phosphono)methyl)phenyl)hex-5-enoyl)-4-benzyl-1,3-oxazolidin-2-one 
• 510773-81-6 (4S)-3-((3S)-6-hydroxy-3-(4-((bis-(tert-butyl)phosphono)methyl)phenyl)hexanoyl)-4-benzyl-1,3-oxazolidin-2-one 
• 510773-82-7 (4-{(R)-1-[(S)-1-Azido-2-((S)-4-benzyl-2-oxo-oxazolidin-3-yl)-2-oxo-ethyl]-4-oxo-butyl}-benzyl)-phosphonic acid di-tert-butyl ester 
• 525575-17-1 1-((4S)-2-oxo-4-benzyl(1,3-oxazolidin-3-yl))-(2S,3R)-2-azido-6-hydroxy-3-(4-((bis-(tert-butyl)phosphono)methyl)phenyl)hexan-1-one 
• 510773-78-1 (2S,3R)-1-((fluoren-9-ylmethyl)oxycarbonyl)-3-(4-((bis-(tert-butyl)phosphono)methyl)phenyl)piperidine-2-carboxylic acid 
• 525575-15-9 (4S)-3-((3S)-3-(4-((bis-(tert-butyl)phosphono)methyl)phenyl)-6-(1,1,2,2-tetramethyl-1-silapropoxy)hexanoyl)-4-benzyl-1,3-oxazolidin-2-one 
• 525575-16-0 1-((4S)-2-oxo-4-benzyl(1,3-oxazolidin-3-yl))-(2S,3R)-2-azido-3-(4-((bis-(tert-butyl)phosphono)methyl)phenyl)-6-(1,1,2,2-tetramethyl-1-silapropoxy)hexan-1-one 
• 525575-18-2 2-{1-[2-carbamoyl-1-(3-naphthalen-1-yl-propylcarbamoyl)-ethylcarbamoyl]-cyclohexylcarbamoyl}-3-[4-(di-tert-butoxy-phosphorylmethyl)-phenyl]-piperidine-1-carboxylic acid 9H-fluoren-9-ylmethyl ester 

Relevant academic research and scientific papers

Synthesis of N-Fmoc 3-(4-(di-(tert-butyl)phosphonomethyl)-phenyl)pipecolic acid as a conformationally constrained phosphotyrosyl mimetic suitably protected for peptide synthesis

Phosphonomethylphenylalanine (Pmp, 2) has shown wide utility as a hydrolytically stable phosphtyrosyl (pTyr, 1) mimetic, particularly in Src homology 2 (SH2) domain-binding peptides. (2S,3R)-3-(4-(phosphonomethyl)phenyl)pipecolic acid (3) represents a var