5260-37-7

Usage

Chemical Properties

yellow crystalline powder

InChI:InChI=1/C10H12NO/c1-3-11-8(2)12-10-7-5-4-6-9(10)11/h4-7H,3H2,1-2H3/q+1

Upstream product

• 95-21-6 2-methyl-1,3-benzoxazole 
• 75-03-6 ethyl iodide 

Downstream Products

• 905-96-4 3,3'-diethyloxacarbocyanine iodide 
• 89748-09-4 4-[(3-ethyl-3H-benzoxazol-2-yliden)-ethylidene]-2-phenyl-4H-oxazol-5-one 
• 14183-74-5 4-[(3-ethyl-3H-benzoxazol-2-yliden)-ethylidene]-5-methyl-2-phenyl-2,4-dihydro-pyrazol-3-one 
• 15185-43-0 3,3'-diethyloxatricarbocyanine iodide 
• 5217-54-9 2-[4-(N-acetyl-anilino)-buta-1,3-dienyl]-3-ethyl-benzoxazolium; iodide 
• 6992-73-0 2-[2-(acetylphenylamino)vinyl]-3-ethylbenzoxazolium iodide 
• 15185-40-7 bis-(3-ethyl-benzoxazol-2-yl)-methinium ; iodide 
• 68700-32-3 2-(4-benzooxazol-2-ylmethylene-5-methyl-2-phenyl-2,4-dihydro-pyrazol-3-ylidenemethyl)-3-ethyl-benzooxazolium; iodide 
• 27051-79-2 3-Ethyl-2-methoxy-2-methyl-benzoxazolin 
• 27051-78-1 2-Ethoxy-3-ethyl-2-methyl-benzoxazolin 
• 909-63-7 3,3',9-triethylthiacarbocyanine iodide 
• 27051-81-6 3-ethyl-2-[2-(N-ethyl-2-hydroxy-anilino)-propenyl]-benzooxazolium; iodide 
• 24136-83-2 2-<ω-Acetanilido-Δ^1,3,5-hexatrienyl-(1)>-N-ethyl-oxazolium-iodid 
• 94724-63-7 3-Ethyl-2-[3-methyl-5-oxo-1-phenyl-1,5-dihydro-pyrazol-(4Z)-ylidenemethyl]-benzooxazol-3-ium; iodide 

Relevant academic research and scientific papers

Fluorescent dye, preparation method and applications thereof

The invention belongs to the technical field of organic synthesis, and particularly relates to a fluorescent dye, a preparation method and applications thereof, wherein the fluorescent dye has a structural general formula represented by a formula I defined in the specification, X and Y are the same or different O, S, C(CH3)2 or NR6, R2 and R3 are the same or different hydrogen or functional groups, R1, R4, R5 and R6 are all functional groups, and Z is a negative ion. According to the present invention, the fluorescent dye has living cell membrane permeability, can be used for fluorescence imaging of living cell microstructures, and can obtain STED super-resolution fluorescence imaging, laser confocal imaging and other fluorescence imaging of living cells.

Conjugating a cyanine dye to a polymer surface. In search of a monomeric dye in apolar media

(Chemical Equation Presented) Solution and solid-phase syntheses of a cyanine dye conjugated to polystyrene beads (desired for potentially interesting electronic properties) are described.

Synthesis and spectroscopic characterisation of N-alkyl quaternary ammonium salts typical precursors of cyanines

The synthesis and spectroscopic characterisation of some representative N-alkyl-substituted quaternary ammonium salts derived from benzothiazole, benzoxazole, benzo-selenazole, indole and quinoline are described. These heterocyclic salts, bearing an activated methyl group in the 2-position in relation to the nitrogen atom and N-methyl, -pentyl, -hexyl and -decyl chains, are typical precursors of cyanine dyes.

A New Method for the Synthesis of Heptamethine Cyanine Dyes: Synthesis of New Near-Infrared Fluorescent Labels

A new uncatalyzed synthesis of heptamethine cyanine dyes is described.The reaction involves heating a mixture of N-alkyl-substituted quaternary salts derived from 2,3,3-trimethylindole or 2,3,3-trimethylbenzindole and 2-chloro-1-formyl-3-(hydroxymethylene)cyclohex-1-ene to reflux in a mixture of 1-butanol and benzene (7:3) as solvent.No catalyst is used, and water is removed as an azeotrope.The resulting chloro compounds possess strong absorption and fluorescence properties in the near-infrared region and are converted to dyes bearing reactive functionalities such as hydroxy and isothiocyanate groups useful as fluorescent tags for nucleic acids and proteins.Several symmetric and nonsymmetric dyes have been synthesized in high yields.