52600-91-6

Basic information

• Product Name: 3-Ethoxyacetophenone
• Synonyms: 3-ethoxyacetophenone;1-(3-ethoxyphenyl)ethanone;1-(3-ethoxyphenyl)ethanone(SALTDATA: FREE)
• CAS NO: 52600-91-6
• Molecular Formula: C₁₀H₁₂O₂
• Molecular Weight: 164.2
• Mol File: 52600-91-6.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 245.1 °C at 760 mmHg
• Flash Point: 98.9 °C
• Appearance: /
• Density: 1.016 g/cm³
• Vapor Pressure: 0.0292mmHg at 25°C
• Refractive Index: 1.501
• CAS DataBase Reference: 3-Ethoxyacetophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Ethoxyacetophenone(52600-91-6)
• EPA Substance Registry System: 3-Ethoxyacetophenone(52600-91-6)

Safety Data

• Hazardous Substances Data: 52600-91-6(Hazardous Substances Data)

Usage

General Description

3-Ethoxyacetophenone, also known as ethyl 3-acetylphenyl ether, is a chemical compound with the molecular formula C10H12O2. It is a colorless liquid with a sweet, floral odor and is commonly used in the production of perfumes and flavors. This chemical is also used as an intermediate in the synthesis of pharmaceuticals and other organic compounds. It is classified as a ketone and contains an ethoxy group, which makes it soluble in organic solvents. 3-Ethoxyacetophenone is considered to be relatively stable under normal conditions and is not known to pose significant health hazards when handled and used properly.

InChI:InChI=1/C10H12O2/c1-3-12-10-6-4-5-9(7-10)8(2)11/h4-7H,3H2,1-2H3

Upstream product

• 22924-15-8 3-ethoxybenzaldehyde 
• 103386-84-1 3-ethoxy ethylbenzene 
• 75-03-6 ethyl iodide 
• 74-96-4 ethyl bromide 
• 121-71-1 3-Hydroxyacetophenone 
• 64-17-5 ethanol 
• 932-66-1 1-cyclohexenyl methyl ketone 

Downstream Products

• 121-71-1 3-Hydroxyacetophenone 
• 1351823-46-5 4-(5-bromothiophen-2-yl)-6-(3-ethoxyphenyl)-2,2'-bipyridine 
• 1351823-49-8 4-(5-(6-(3-ethoxyphenyl)-2,2'-bipyridin-4-yl)thiophen-2-yl)-N,N-bis(4-methoxyphenyl)aniline 
• 1351823-48-7 4-(5-(6-(3-ethoxyphenyl)-2,2'-bipyridin-4-yl)thiophen-2-yl)-N,N-diphenylaniline 
• 1351823-44-3 1-(2-(3-ethoxyphenyl)-2-oxoethyl)pyridinium iodide 
• 905592-32-7 4-(3-ethoxyphenyl)-4-oxobutanoic acid ethyl etser 
• 70460-18-3 3'-hydroxyflavone 

Relevant articles and documents

Synthesis of chiral γ-lactones via a RuPHOX-Ru catalyzed asymmetric hydrogenation of aroylacrylic acids

An asymmetric hydrogenation of aroylacrylic acids catalyzed by RuPHOX-Ru catalyst has been developed, affording the corresponding chiral γ-lactones in high yields and with up to 93% ee. The methodology has the advantage of utilizing easily accessible substrates and has therefore expand the scope of the resulting chiral γ-lactones. Furthermore, high catalytic efficiency was achieved in that the reduction of both the C[dbnd]C and C[dbnd]O double bonds was achieved in one step. The current work provides an alternative and convenient pathway for the synthesis of a wide range of chiral γ-lactones.

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One pot synthesis of α-ketoamides from ethylarenes and amines: a metal free difunctionalization strategy

One-pot and metal free synthesis of α-ketoamides has been described through in situ generation of aryl ketones from easily available ethylarenes followed by amidation with various amines. This multiple oxidation protocol involves catalytic I2-pyridine-TBHP (t-butyl hydroperoxide) mediated oxidative benzylic carbonylation and sequential NaI-TBHP mediated oxidative amidation without using any solvent.