52601-60-2

Upstream product

• 99-90-1 para-bromoacetophenone 
• 135-02-4 ortho-anisaldehyde 

Downstream Products

• 898769-87-4 1-(4-bromophenyl)-3-(2-methoxyphenyl)propan-1-one 
• 6607-94-9 4'-hydroxy-2-methoxychalcone 
• 400031-87-0 7-(4-bromo-phenyl)-3,5-bis-(2-methoxy-phenyl)-2-thioxo-2,3-dihydro-1H-pyrido[2,3-d]pyrimidin-4-one 
• 400031-69-8 2-amino-6-(4-bromo-phenyl)-4-(2-methoxy-phenyl)-nicotinamide 

Relevant academic research and scientific papers

Synthesis, spectroscopic characterization, and computed optical analysis of green fluorescent cyclohexenone derivatives

Cyclohexenone containing chalcones core is one important class of materials, which exhibit high nonlinear optical (NLO) responses and good crystallizability. The present study reports the successful development of six new fluorescent cyclohexenone derivat

Transition metal-free domino aryl-aryl coupling/phospha-Michael addition of diarylphosphinite to α,β-unsaturated ketones triggered by alkaline hydrolysis of (4-(2-alkenoyl)phenyl)triarylphosphonium salts

Alkaline hydrolysis of a variety of (4-(2-alkenoyl)phenyl)triarylphosphonium bromides is reported. This hydrolysis triggers coupling of 4-(2-alkenoyl)phenyl with one aryl via phosphorus(V). Both diarylphosphinite and an α,β-unsaturated ketone are in situ generated and then undergo phospha-Michael addition to provide β-diarylphosphoryl ketones bearing a biaryl moiety in 27–70% yields in the absence of a transition metal.

Iron-Catalyzed Chemoselective Reduction of α,β-Unsaturated Ketones

An iron-catalyzed chemo- and diastereoselective reduction of α,β-unsaturated ketones into the corresponding saturated ketones in mild reaction conditions is reported herein. DFT calculations and experimental work underline that transfer hydride reduction is a more facile process than hydrogenation, unveiling the fundamental role of the base.