52607-63-3

Upstream product

• 2684-02-8 benzenediazonium 
• 148-53-8 3-methoxy-2-hydroxybenzaldehyde 
• 98-47-5 3-Nitrobenzenesulfonic acid 
• 3153-97-7 2-methoxy-4,6-bishydroxymethyl phenol 
• 62-53-3 aniline 
• 877-22-5 3-methoxysalicylic acid 

Downstream Products

• 102893-23-2 4-(2-acetoxy-3-methoxy-5-phenylazo-benzylidene)-2-phenyl-4H-oxazol-5-one 
• 100969-90-2 2,3-dimethoxy-5-phenylazo-benzaldehyde 
• 52607-61-1 8-methoxy-1',3',3'-trimethyl-6-phenylazo-1',3'-dihydro-spiro[chromene-2,2'-indole] 
• 52607-58-6 8-methoxy-5'-methyl-6-phenylazo-5'H-spiro[chromene-2,6'-phenanthridine] 
• 1357568-80-9 3-acetyl-8-methoxy-6-(phenyldiazenyl)-2H-chromen-2-one 

Relevant academic research and scientific papers

Synthesis and antibacterial evaluation of diaminomaleonitrile-based azo-Schiff bases and 8,9-dihydro-7H-purine-6-carboxamides

Some new DAMN-based Schiff base 6a–6g were synthesized via a condensation reaction of the corresponding azo dyes with 1-(2-amino-1,2-dicyanovinyl)-3-phenylurea. In continuation, facile synthesis of new 8,9-dihydro-7H-purine-6-carboxamide 7a–7g was reported via an efficient reaction of azo dyes and 1-(2-amino-1,2-dicyanovinyl)-3-phenylurea in the presence of triethylamine as catalyst. All the synthesized compounds were evaluated for their antibacterial activities against both Gram-positive (Micrococcus luteus and Staphylococcus aureus) and Gram-negative (Pseudomonas aeruginosa and Escherichia coli) bacteria.

Synthesis of an azo-Mn(II) complex with mild pH control using a microfluidic device

This study describes the synthesis of an azo-Mn(ii) complex requiring an accurate pH control. The reaction conditions for the delicate azo-Mn(ii) complex could be precisely controlled using a microfluidic device. The microfluidic method showed the followi

Transition Metal (II) Complexes with a Novel Azo-azomethine Schiff Base Ligand: Synthesis, Structural and Spectroscopic Characterization, Thermal Properties and Biological Applications

The pyrimidine based azo-linked Schiff base ligand, 5-benzoyl-1-((E)-(2-hydroxy-3-methoxy-5-((E)phenyldiazenyl)benzylidene)amino)-4-phenylpyrimidin-2(1H)-one (HL), and its transition metal (II) complexes were synthesized and defined by using 1H-NMR, 13C-NMR, Elemental analysis, FT-IR, MS, UV–vis, molar conductance, magnetic susceptibility and thermal analysis techniques. According to the conductance data obtained indicate all of the metal complexes have non-electrolytic nature. Square pyramidal geometry for Pd(II) and octahedral geometry for all the other complexes synthesized was concluded from the electronic absorption spectra and magnetic susceptibility measurements of the complexes. Investigation of the significant infrared bands of the active groups in the ligand and the solid complexes alludes that HL is coordinated to the metal ions ONO tridentate manner. Moreover, the absorption and emission properties of the azo-azomethine based ligand and its complexes were investigated. The results obtained show that fluorescence emissions of the ligand and its metal (II) complexes depend on the type of transition metal ions and the derivatives displayed moderate Stokes’ shift values between 44 and 107?nm. All the compounds exhibited superb photostability. Further, antioxidant, antimicrobial and pBR322 plasmid DNA cleavage activities were investigated. All compounds showed good DPPH? (1,1-diphenyl-2-picrylhydrazyl) radical scavenging activity and complexes of [MnL2]?H2O and [NiL2]?H2O exhibited excellent metal chelating activity. All the compounds tested demonstrated two strand DNA cleavage activities.

Azo-Label Heterometal-Organic Rhomboids Exhibiting Photoswitchable NIR Luminescence in Crystalline State

Photochromism is an important strategy for realizing reversible light-controllable fluorescence switching. In spite of several reports on fluorescence switching via a photochromic process, the success of photochromic multimetallic complexes reversibly showing fluorescence switching in the solid or crystalline state has been limited for their application importance. Here, we report a photoswitchable near-infrared (NIR) fluorescence based on photochromism in the azo-label 3d/4f heterometal-organic rhomboids, azo-Zn2Ln2 (Ln = Eu (1), Yb (2), and Er (3)), in the crystalline state. An individual metallorhomboid contains up to four azobenzene fragments, which is prepared via the three-component assembly of a trans-azobenzene-grafted multifunctional ligand, and 3d and 4f metal ions. The photoisomerization quantum yields of azo-Zn2Ln2 complexes can be retained or even higher when compared to the free ligand due to the modification of electronic structure. The impressive crystalline-state NIR luminescence is observed for the complexes of azo-Zn2Yb2 (2) and azo-Zn2Er2 (3) at room temperature. Intriguingly, the switchable NIR luminescence can be effectively regulated by photochromism in the crystalline state. These features endow the self-assembly of the 3d/4f metallorhomboid with synergetic multifunctional behavior between photochromism and NIR luminescence.

Microdroplet synthesis of azo compounds with simple microfluidics-based pH control

Conventional solution-phase synthesis of azo compounds is complicated by the need for precise pH and temperature control, high concentrations of pH control reagents, and by-product removal. In this work, we exploited the advantages of microdroplet chemist

Novel bioactive azo-azomethine based Cu (II), Co (II) and Ni(II) complexes, structural determination and biological activity

A novel bioactive azo-azomithine tridentate ligand N'-(E)-{2-hydroxy-3-methoxy-5-[(E)phenyldiazenyl]phenyl}methylidene]pyridine-3 carbohydrazide (HL) and its Cu(II), Co(II) and Ni(II) complexes were synthesized and their structure determined by elemental

Sustainable synthesis of [1]benzopyran azo dyes using CuCr2O4 NPs

In this study, copper chromite nanoparticles (CuCr2O4 NPs) were prepared by a simple hydrothermal method. This nanomaterial was found as an efficient heterogeneous catalyst for the synthesis of a new class of [1]benzopyran azo dyes v

Synthesis of MnII and CuII complexes including azobenzene and its application to mediators of laccase for biofuel cells

Laccase is mainly used as an enzyme of a cathode electrode of a biofuel cell. One problem is rate limiting of electron transfer between electrodes and enzymes. To enhance transfer of electron from the electrode to the redox center in the enzyme, using med

Synthesis of new bis-benzylidene-hydrazides as a sensitive chromogenic sensor for naked-eye detection of CNˉ and AcOˉ ions

Some new bis-benzylidene-hydrazides were synthesized via a condensation reaction of the corresponding azo dyes with adipic acid dihydrazide. All compounds because of the three possible stereoisomers showed four sets of signals in NMR. The anion recognition studies exhibited that the nitro bis-benzylidene-hydrazide derivative acts as a highly sensitive and selective chromogenic sensor for naked-eye detection of CNˉ and AcOˉ ions, with a distinct color change from yellow to blue and yellow to purple, respectively. The limit of detection (LOD) was found for 1d toward CNˉ to be 1.1 μM. The result of the Job's plot indicated stoichiometry of binding between chemosensor and anions is found to be 1:2.

Microwave-assisted synthesis and photochromic properties of new azo-imidazoles

A convenient, one-pot three-component synthesis of new photochromic azo-imidazoles (1a-1h) from the corresponding azo dyes (2a-2h), benzil and ammonium acetate under microwave irradiation were described and their photochromic properties were investigated.