70854-63-6

Upstream product

• 66958-69-8 1,4-bis(benzyloxy)-2-[(2E)-4-bromo-3-methylbut-2-enyl]-5,6-dimethoxy-3-methylbenzene 
• 70854-64-7 solanesyl p-tolyl sulphone 
• 52610-77-2 solanesyl bromide 
• 13190-97-1 solanesol 
• 66958-67-6 1,4-bis(benzyloxy)-2,3-dimethoxy-5-methyl-6-(3-methylbut-2-enyl)benzene 
• 70238-42-5 (2E)-4-[2,5-bis(benzyloxy)-3,4-dimethoxy-6-methylphenyl]-2-methylbut-2-en-1-ol 
• 727-81-1 2,3-dimethoxy-5-methyl-6-(3-methyl-2-butenyl)-1,4-benzoquinone 
• 52590-98-4 1-ubiquinol 
• 911125-73-0 (E)-4-(2,5-Bis-benzyloxy-3,4-dimethoxy-6-methyl-phenyl)-2-methyl-but-2-enal 

Downstream Products

• 303-98-0 ubidecarenone 
• 94827-96-0 2-((2E,5E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-Decamethyl-tetraconta-2,5,10,14,18,22,26,30,34,38-decaenyl)-5,6-dimethoxy-3-methyl-[1,4]benzoquinone 
• 75426-26-5 ubiquinol 

Relevant academic research and scientific papers

Synthetic studies on coenzyme Q10: Part 2 - A efficient and improved synthesis of coenzyme Q10 via the C5 + C 45 approach

An improved route to coenzyme Q10 (1) starting from commercially available coenzyme Q1 is described. The key steps in this synthesis are the SeO2-mediated oxidation of the protected isoprenylhydroquinone 3 into the (E)-allyl alcohol 5 without the formation of undesired stereoisomer and the one-pot reductive elimination of the phenylsulfonyl and dibenzyl groups in 7 by using naphthalenyllithium.

Synthetic Studies on Isoprenoidquinones. II. Syntheses of Ubiquinone-10, Phylloquinone, and Menaquinone-4 by a Chain-Extending Method Utilizing Terminally Functionalized Isoprenoidhydroquinones

Physiologically active polyisopreoidquinones, ubiquinone-10 (coenzyme Q10), phylloquinone (vitamin K1), and menaquinone-4 (vitamin K2(20)) were synthesized by a chain-extending method utilizing protected hydroquinones with the omega-hydroxyprenyl or omega-hydroxygeranyl side chain.Conditions for reductive desulfurization subsequent to allylic homologation was investigated. Keywords - polyisoprenoidquinone synthesis; ubiquinone-10; phylloquinone; menaquinone-4; chain-extending method; sulfone coupling; reductive desulfurization