526211-18-7Relevant articles and documents
Synthesis of 1- and 3-chloro-phenothiazines
Kumar, Gulshan,Gupta, Vandana,Gautam,Gupta
, p. 447 - 450 (2002)
Phenothiazines have been synthesized via Smiles rearrangement by the reaction of 2-amino-3/5-chlorobenzenethiols with halonitrobenzenes. Halonitrobenzenes having a nitro group at both ortho positions to halogen yields directly phenothiazines as Smiles rearrangement occurs insitu. Halonitrobenzenes having a nitro group at ortho position to halogen give 2-amino-2′-nitrodiphenylsulfides which on formylation with 90% formic acid yields 2-formamido-2′-nitrodiphenylsulfides, which undergo Smiles rearrangement to provide phenothiazines.