52634-47-6Relevant academic research and scientific papers
Selective reduction of peptide isothiazolidin-3-ones
Shiau, Timothy P.,Erlanson, Daniel A.,Gordon, Eric M.
, p. 5697 - 5699 (2006)
(Diagram presented) Isothiazolidinones are a rare but potentially important chemical moiety in biochemistry. We report the identification of several thiol, phosphinate, and carbon nucleophiles that form covalent adducts by addition to the sulfenamide sulf
Profiling the reactivity of cyclic C-nucleophiles towards electrophilic sulfur in cysteine sulfenic acid
Gupta, Vinayak,Carroll, Kate S.
, p. 400 - 415 (2015/12/30)
Oxidation of a protein cysteine thiol to sulfenic acid, termed S-sulfenylation, is a reversible post-translational modification that plays a crucial role in regulating protein function and is correlated with disease states. The majority of reaction-based
