52678-80-5

Upstream product

• 100-02-7 4-nitro-phenol 
• 72448-65-8 Thiophosphorsaeure-O,O-bis-<4-nitro-phenylester> 

Downstream Products

• 104110-05-6 Thiophosphoric acid O-[(2R,3S,4R,5R)-5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-3,4-dihydroxy-tetrahydro-furan-2-ylmethyl] ester O',O''-bis-(4-nitro-phenyl) ester 
• 332095-13-3 thiophosphoramidic acid O,O'-bis-(4-nitro-phenyl) ester 
• 104110-04-5 Thiophosphoric acid O-[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3,4-dihydroxy-tetrahydro-furan-2-ylmethyl] ester O',O''-bis-(4-nitro-phenyl) ester 
• 104110-06-7 Thiophosphoric acid O-((2R,3S,4R,5R)-3,4-dihydroxy-5-{2-[(Z)-isobutyrylimino]-6-oxo-1,2,3,6-tetrahydro-purin-9-yl}-tetrahydro-furan-2-ylmethyl) ester O',O''-bis-(4-nitro-phenyl) ester 

Relevant academic research and scientific papers

Design and synthesis of novel active phosphonate esters and their application in preparation of ceftriaxone

For a series of active phosphonate esters, the anhydride abbreviated as ANPTA (6a) exhibits the highest reactivity in the preparation of ceftriaxone. The synthesis of ceftriaxone was optimized with the pilot-scale yield reaching 95.7%. The results were explained from the structural viewpoint and supported by analysis of the calculated Mulliken atomic charge distribution.

The synthesis and evalution of novel aryl-substituted dithioimidophosphonates as an extrantant for metals

A novel series of O,O′,O″,O?- tetraaryldithioimidophonates [(ArO)2PS]2NH 4 were synthesized by the reaction of O,O,-diaryl phosphorochlorothionates 2 and diarylphosphonothioic amide under a strong basic condition. The key intermediat

Phase-Transfer Reactions of Phosphorus Thiochloride with Phenols in the System Liquid-Solid Phase

Preparative syntheses of aryl phosphorodichloridothioates and 2-propynyl phosphorodichloridothioates via phase-transfer reactions of phosphorus thiochloride with phenols in the presence of solid bases were developed.

SYNTHESIS OF O-ARYL DICHLOROTHIOPHOSPHATES VIA PHASE-TRANSFER CATALYSIS

A convenient general method for synthesis of aryl dichlorothiophosphates via phase-transfer catalysis was developed.An influence of the reaction conditions on the yields and purity of the compounds synthesized was studied.