52679-49-9 Usage
General Description
Benzenepropanoic acid, 2-bromo-4,5-dimethoxy- (9CI) is a chemical compound that is used in organic synthesis. It is a derivative of benzenepropanoic acid and contains a bromine atom as well as two methoxy groups. Benzenepropanoic acid, 2-bromo-4,5-dimethoxy- (9CI) may have potential uses in pharmaceutical and medicinal chemistry due to its structure and properties. However, it is important to handle and use this chemical with care as it may have hazardous effects if not properly managed.
Check Digit Verification of cas no
The CAS Registry Mumber 52679-49-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,6,7 and 9 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 52679-49:
(7*5)+(6*2)+(5*6)+(4*7)+(3*9)+(2*4)+(1*9)=149
149 % 10 = 9
So 52679-49-9 is a valid CAS Registry Number.
InChI:InChI=1/C11H13BrO4/c1-15-9-5-7(3-4-11(13)14)8(12)6-10(9)16-2/h5-6H,3-4H2,1-2H3,(H,13,14)
52679-49-9Relevant articles and documents
Palladium-catalyzed cross-coupling reactions in one-pot multicatalytic processes
Lebel, Helene,Ladjel, Chehla,Brethous, Lise
, p. 13321 - 13326 (2008/09/17)
Palladium-catalyzed cross-coupling reactions have been investigated in multicatalytic processes to synthesize disubstituted alkenes and alkanes from carbonyl derivatives. The use of copper-catalyzed methylenation reactions is the key starting reaction to produce terminal alkenes which are not isolated, but submitted to further structure elongation. Not only is the isolation of the alkene intermediate unnecessary, but also the copper catalyst is a beneficial cocatalyst in the palladium-catalyzed cross-coupling reactions. The desired products are thus typically obtained in higher yields using this one-pot approach. We have used these processes to synthesize hydroxylated (E)-stilbenoids, which are known chemopreventive and chemotherapeutic agents, odorant-substituted indanes, and non-natural amino acids, such as homophenylalanine.