52708-38-0

Usage

Type of compound

nitrophenyl-substituted tetrazole derivative

Common uses

high-energy material, propellant for gas generators, component in explosive formulations

Known for

high thermal stability, energy release

Potential uses

pharmaceuticals, other energetic materials

Safety

handle with care, follow proper safety protocols

Upstream product

• 56476-95-0 2-phenyl-2H-tetrazole 
• 288-94-8 1H-tetrazole 
• 350-46-9 4-Fluoronitrobenzene 
• 456-27-9 4-nitrobenzenediazonium tetrafluoroborate 
• 100-01-6 4-nitro-aniline 

Downstream Products

• 52708-35-7 2-(4-aminophenyl)-2H-tetrazole 
• 64001-12-3 4-(2H-tetrazol-2-yl)phenol 

Relevant academic research and scientific papers

Synthesis of 2-aryl-2H-tetrazoles via a regioselective [3+2] cycloaddition reaction

A regioselective cycloaddition reaction of arenediazonium salts with trimethylsilyldiazomethane is reported. A series of 2-aryltetrazoles were obtained in good to moderate yields with wide functional group compatibility. Furthermore, this cycloaddition reaction opens the way to build up the versatile intermediate 2-aryl-5-bromotetrazole.

IMINOSUGARS USEFUL FOR THE TREATMENT OF VIRAL DISEASES

Formula IA, ad their use for treating viral infections.

HIV PROTEASE INHIBITORS

Compounds of Formula I are disclosed: wherein A, R1, R2, R3, R4A, R4B, R5, R6 and R7 are defined herein. The compounds encompassed by Formula I include compounds which

SUBSTITUTED CYCLOPROPYL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT

Substituted cyclopropyl compounds of formula (I) are disclosed as useful for treating or preventing type 2 diabetes and similar conditions. Pharmaceutically acceptable salts and solvates are included as well. The compounds are useful as agonists of the g-protein coupled receptor GPR-119.