5274-40-8Relevant academic research and scientific papers
Synthesis, structures and preliminary biological screening of bis(diphenyl)chlorotin complexes and adducts: Ph2ClSn-CH 2-R-CH2-SnClPh2, R = p-C6H 4, CH2CH2
Thodupunoori, Srawan K.,Alamudun, Israel A.,Cervantes-Lee, Francisco,Gomez, Fabiola D.,Carrasco, Yazmin P.,Pannell, Keith H.
, p. 1790 - 1796 (2006)
The reaction between ClCH2-R-CH2Cl, R = p-C 6H4, and [Ph3Sn]-Li+ yields Ph3Sn-CH2-R-CH2-SnPh3 (1) in high yield. The related known compound R = CH2CH2 (1a) is synthesized by the reaction of the di-Grignard reagent BrMg(CH2) 4MgBr with two equivalents of Ph3SnCl. Cleavage of a single Sn-Ph group at each tin centre of both compounds using HCl/Et 2O yields the corresponding bis-chlorostannanes Ph 2ClSn-CH2-R-CH2-SnClPh2, R = (CH2)4 (2) and R = C6H4 (3), respectively. Compounds 1, 2 and 3 are crystalline solid materials and their single crystal X-ray structures are reported. In the solid state both 2 and 3 form self-assembled ladder structures involving alternating intermolecular Cl-Sn?Cl and Cl?Sn-Cl bonded chains at both ends of the distannanes with 5-coordinate tin atoms. Recrystallization of 3 from CH 2Cl2 in the presence of DMF yields the bis-DMF adduct (4) in which no self-assembled structures were noted. Evaluation of the chlorostannanes 2 and 3 against a suite of bacteria, Staphylococcus aureus, Escherichia coli and Photobacterium phosphoreum is reported and compared to the related mono-chlorostannanes Ph2(CH3)SnCl and Ph 2(PhCH2)SnCl.
Macrocycles containing tin. Two syntheses of 1, 1, 6, 6, 11, 11, 16, 16-octaphenyl-1, 6, 11, 16-tetrastannacycloeicosane and a synthesis of 1, 1, 6, 6-tetraphenyl-1, 6-distannacyclodecane
Newcomb, Martin,Azuma, Yutaka,Courtney, Arlene R.
, p. 175 - 177 (1983)
The title syntheses are described. The synthetic and purification and analytical methods employed are of general utility for the preparation and functionalization of members of this class of compounds.
