52787-46-9

Upstream product

• 6066-82-6 1-hydroxy-pyrrolidine-2,5-dione 
• 1490-25-1 succinic acid monomethylester chloride 

Downstream Products

• 128217-68-5 N-[2-(3,4-Bis-benzyloxy-phenyl)-1-ethoxycarbonyl-ethyl]-succinamic acid methyl ester 
• 128217-72-1 3-(3,4-Bis-benzyloxy-phenyl)-2-(2,5-dioxo-pyrrolidin-1-yl)-propionic acid methyl ester 
• 128217-71-0 3-(3,4-Bis-benzyloxy-phenyl)-2-(2,5-dioxo-pyrrolidin-1-yl)-propionic acid ethyl ester 
• 128217-69-6 N-[2-(3,4-Bis-benzyloxy-phenyl)-1-methoxycarbonyl-ethyl]-succinamic acid methyl ester 
• 128217-70-9 N-[2-(3,4-Bis-benzyloxy-phenyl)-1-ethoxycarbonyl-ethyl]-succinamic acid ethyl ester 
• 92279-28-2 4-<(methoxysuccinyl)-L-alanyl-L-alanyl-L-prolinamido>phenyl N,N-dimethylcarbamate 
• 92279-29-3 4-<(methoxysuccinyl)-L-alanyl-L-alanyl-L-prolinamido>phenyl N-isopropylcarbamate 
• 92279-33-9 phenyl N-<(methoxysuccinyl)-L-alanyl-L-alanyl-L-prolylmethyl>-N-isopropylcarbamate 
• 102284-59-3 S-benzyl N-<(methoxysuccinyl)-L-alanyl-L-alanyl-L-prolylmethyl>-N-isopropylcarbamate 
• 92279-31-7 DL-2-<(methoxysuccinyl)-L-alanyl-L-alanyl-L-prolinamido>-3-methyl-1-butyl N-phenylcarbamate 
• 92279-27-1 4-<(methoxysuccinyl)-L-alanyl-L-alanyl-L-prolinamido>phenyl N-phenylcarbamate 
• 92279-30-6 2-<(methoxysuccinyl)-L-alanyl-L-alanyl-L-prolinamido>phenyl N-phenylcarbamate 
• 102284-62-8 N-<(methoxysuccinyl)-L-alanyl-L-alanyl-L-prolylmethyl>-N-isopropyl-N'-(p-nitrophenyl)urea 
• 92279-32-8 p-nitrophenyl N-<(methoxysuccinyl)-L-alanyl-L-alanyl-L-prolylmethyl>-N-isopropylcarbamate 

Relevant academic research and scientific papers

Antibodies to Olanzapine Haptens and Use Thereof

Disclosed is an antibody which binds to olanzapine, which can be used to detect olanzapine in a sample such as in a competitive immunoassay method. The antibody can be used in a lateral flow assay device for point-of-care detection of olanzapine, including multiplex detection of aripiprazole, olanzapine, quetiapine, and risperidone in a single lateral flow assay device.

ANTIBODIES TO OLANZAPINE HAPTENS AND USE THEREOF

Disclosed is an antibody which binds to olanzapine, which can be used to detect olanzapine in a sample such as in a competitive immunoassay method. The antibody can be used in a lateral flow assay device for point-of-care detection of olanzapine, including multiplex detection of aripiprazole, olanzapine, quetiapine, and risperidone in a single lateral flow assay device.

HAPTENS OF OLANZIPINE

The invention relates to compounds of Formula I, wherein R1, R2, and R3 are defined in the specification, useful for the synthesis of novel conjugates and immunogens derived from olanzapine. The invention also relates to conjugates of an olanzapine hapten and a protein.

Peptidyl Carbamates Incorporating Amino Acid Isosteres as Novel Elastase Inhibitors

The design and synthesis of 13 novel peptidyl carbamates are described.When tested for inhibitory activity toward porcine pancreatic elastase, trypsin, and chymotrypsin, six compounds were found to specifically inhibit lastase without affecting the other