52789-91-0

Usage

Uses

Used in Pharmaceutical Industry:
(5-BROMO-1-BENZOFURAN-2-YL)(4-METHYLPHENYL)METHANONE is used as a compound with potential pharmaceutical applications due to its unique structural features that can be utilized for the development of new drugs.
Used in Organic Synthesis:
(5-BROMO-1-BENZOFURAN-2-YL)(4-METHYLPHENYL)METHANONE is used as a precursor in organic synthesis for the synthesis of other organic compounds, taking advantage of its distinctive chemical structure.

Upstream product

• 7645-95-6 (E)-3-(2-hydroxyphenyl)-1-(4-methylphenyl)-2-propen-1-one 
• 40805-62-7 2-iodo-1-(4-methylphenyl)ethanone 
• 1761-61-1 5-bromosalicyclaldehyde 
• 619-41-0 4-(bromoacetyl)toluene 
• 125418-95-3 2-(4-bromo-2-formylphenoxy)acetonitrile 
• 5720-05-8 4-methylphenylboronic acid 

Relevant academic research and scientific papers

Tandem addition/cyclization for synthesis of 2-aroyl benzofurans and 2-aroyl indoles by carbopalladation of nitriles

The first example of the palladium-catalyzed tandem addition/cyclization of 2-(2-acylphenoxy)acetonitriles with arylboronic acids has been developed, providing a new strategy for the synthesis of 2-aroyl benzofurans with excellent chemoselectivity and wid

DMAP-catalyzed cascade reaction: One-pot synthesis of benzofurans in water

A series of benzofurans were efficiently synthesized in good to excellent yields using 4-dimethylaminopyridine (DMAP) catalyzed cascade reaction between salicylaldehydes and halogenated ketones in water at 80 °C opened atmosphere.

Microwave-mediated solvent free Rap-Stoermer reaction for efficient synthesis of benzofurans

The Rap-Stoermer reaction of salicylaldehydes with diverse phenacyl bromide and phenacyl iodides proceeded cleanly to afford various functionalized benzofurans in excellent yields under base-mediated solvent free microwave irradiation conditions.

Reaction of chalcones with NBS, a simple one pot synthesis of 2-aroylbenzo[b]furanes

A simple one pot synthesis of 2-aroylbenzo[b]furanes has been achieved by bromomethoxylation with NBS and subsequent treatment of the appropriately substituted 2-hydroxychalcones with sodium hydroxide.