52797-55-4

Upstream product

• 33682-61-0 3-benzylbenzo[d]thiazole-2(3H)-thione 
• 76464-99-8 N-benzyl-2-iodoaniline 
• 398469-59-5 2-(N-benzyl)amino-S-benzylthiophenol 
• 6325-92-4 2-(benzylsulfanyl)aniline 
• 883-93-2 2-Phenylbenzothiazole 
• 1408300-21-9 2-amino-S-cinnamylthiophenol 
• 77053-20-4 2-(2-propen-1-ylsulfanyl)aniline 
• 137-07-5 2-amino-benzenethiol 

Downstream Products

• 101786-17-8 (3-benzyl-2-methyl-2,3-dihydro-benzothiazol-2-ylmethyl)-dimethyl-amine 
• 56553-71-0 2,2'-disulfanediylbis(N-benzylaniline) 
• 883-93-2 2-Phenylbenzothiazole 
• 21223-76-7 3-benzyl-2-(4-dimethylamino-phenyl)-benzothiazolium; chloride 
• 102458-15-1 3-benzyl-2-piperidinomethyl-2,3-dihydro-benzothiazole 

Relevant academic research and scientific papers

Copper-catalyzed double c-s bonds formation via different paths: Synthesis of benzothiazoles from n -benzyl-2-iodoaniline and potassium sulfide

A new, highly efficient procedure for the synthesis of benzothiazoles from easily available N-benzyl-2-iodoaniline and potassium sulfide has been developed. The results show copper-catalyzed double C-S bond formation via a traditional cross-coupling reaction and an oxidative cross-coupling reaction.

Synthesis of multidentate ligands via reduction of Schiff base-zinc(II) complex and their use for in situ synthesis of potentially biomimetic Type I copper complexes

In an attempt to simulate the properties of blue copper proteins three low molecular weight and low symmetric solid copper(II) complexes have been synthesized. Ligands with highly ' asymmetric coordination environment have been prepared in two steps. The first step involves synthesis of zinc-coordinated Schiff base of benzothiazolines, which are then subjected to reduction followed by removal of the metal ion from these reduced complexes. The free ligands thus generated are then used for in situ complexation with Cu(II). These complexes exhibit an intense S→Cu(II) charge transfer band at ≈ 600 nm with high extinction values, which is characteristic of Type I copper complexes. The conductivity, magnetic susceptibility and IR studies also support the assigned structures to the complexes.

A new approach to reductive deprotection of thioethers with a low-valent titanium reagent

Low-valent titanium mediated cleavage of carbon-sulphur bond is reported. This has resulted in an efficient and mild protocol for the deprotection of allyl/benzyl thioethers under reductive condition and with good yields. Deprotection can be performed regio- and chemo-selectively in the presence of acid, ester and N-benzyl/allyl functionalities and is general for aliphatic and aromatic precursors.