77053-20-4Relevant articles and documents
Copper-catalyzed carbochlorination or carbobromination via radical cyclization of aryl amines
Ouyang, Jianing,Su, Xiaolong,Chen, Yu,Yuan, Yaofeng,Li, Yi
supporting information, p. 1438 - 1441 (2016/03/12)
A copper-catalyzed radical carbochlorination or carbobromination is reported. Intramolecular cyclization occurred through aryl radicals generated in situ from bench-stable aryl amines with aqueous hydrogen halides as the halogen sources. A variety of (3-h
Transition metal-free activation of allylic acetates toward regioselective S-allylation of thiols
Saha, Amit,Ranu, Brindaban C.
experimental part, p. 1902 - 1905 (2010/09/07)
Allylic acetates have been used as allylating agents under transition metal-free condition toward an economical and sustainable regioselective S-allylation of aromatic and aliphatic thiols in the presence of potassium carbonate in DMF.
Design and synthesis of cinanserin analogs as severe acute respiratory syndrome coronavirus 3CL protease inhibitors
Yang, Qingang,Chen, Lili,He, Xuchang,Gao, Zhenting,Shen, Xu,Bai, Donglu
scheme or table, p. 1400 - 1405 (2009/09/29)
The severe acute respiratory syndrome (SARS) coronavirus 3CL protease is an attractive target for the development of anti-SARS drugs. In this paper, cinanserin (1) analogs were synthesized and tested for the inhibitory activities against SARS-coronavirus (CoV) 3CL protease by fluorescence resonance energy transfer (FRET) assay. Four analogs show significant activities, especially compound 26 with an IC50 of 1.06 μM.
