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2-Hydroxy-3,5-diiodobenzoic acid ethyl ester is an organic compound with the chemical formula C9H8I2O4. It is a derivative of benzoic acid, featuring two iodine atoms at the 3rd and 5th positions, a hydroxyl group at the 2nd position, and an ethyl ester group at the carboxylic acid end. 2-hydroxy-3,5-diiodobenzoic acid ethyl ester is characterized by its potential applications in pharmaceuticals and chemical research, particularly in the synthesis of various organic compounds and as an intermediate in the preparation of iodine-containing drugs. Its molecular structure and functional groups contribute to its unique chemical properties, making it a valuable component in the field of organic chemistry.

528-15-4

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528-15-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 528-15-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,2 and 8 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 528-15:
(5*5)+(4*2)+(3*8)+(2*1)+(1*5)=64
64 % 10 = 4
So 528-15-4 is a valid CAS Registry Number.

528-15-4Relevant academic research and scientific papers

Preparation of functionalized aryl magnesium reagents by the addition of magnesium aryl thiolates and amides to arynes

Lin, Wenwei,Sapountzis, Ioannis,Knochel, Paul

, p. 4258 - 4261 (2007/10/03)

(Chemical Equation Presented) Reactive arynes, which are readily generated by the reaction of ortho-iocloarylsulfonates with iPrMgCl, undergo the smooth addition of various magnesium nucleophiles like magnesium thiolates, selenides, and amides. In all cases the resulting functionalized aryl magnesium species can be trapped by an electrophile leading to highly functionalized aromatic compounds (see scheme).

Iodination of Phenols by Use of Benzyltrimethylammonium Dichloroiodate(1-)

Kajigaeshi, Shoji,Kakinami, Takaaki,Yamasaki, Hiromichi,Fujisaki, Shizuo,Kondo, Manabu,Okamoto, Tsuyoshi

, p. 2109 - 2112 (2007/10/02)

The reaction of phenols with benzyltrimethylammonium dichloroiodate(1-) in dichloromethane-methanol in the presence of CaCO3 or NaHCO3 for several hours at room temperature gave iodophenols in good yields.

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