528-38-1 Usage
Uses
Used in Pharmaceutical Development:
(1α,2β,3α,4β)-2,4-Diphenyl-1,3-cyclobutanedicarboxylic acid is used as a key intermediate in the synthesis of various pharmaceuticals for its unique structure and reactivity. Its ability to form multiple stereochemical configurations allows for the development of chiral molecules with specific biological activities.
Used in Organic Synthesis:
In the field of organic synthesis, (1α,2β,3α,4β)-2,4-Diphenyl-1,3-cyclobutanedicarboxylic acid serves as a versatile building block for the creation of complex organic molecules. Its two phenyl groups and dicarboxylic acid functionality enable the formation of a wide range of compounds with diverse applications.
Used in Medicinal Chemistry:
(1α,2β,3α,4β)-2,4-Diphenyl-1,3-cyclobutanedicarboxylic acid is utilized in medicinal chemistry for the design and synthesis of biologically active molecules. Its unique structure allows for the development of novel drug candidates with potential therapeutic applications.
Used in Research and Development:
In the research and development sector, (1α,2β,3α,4β)-2,4-Diphenyl-1,3-cyclobutanedicarboxylic acid is employed as a valuable compound for studying the effects of stereochemistry on molecular properties and biological activities. Its multiple asymmetric carbon centers provide opportunities for exploring the role of chirality in drug design and development.
Check Digit Verification of cas no
The CAS Registry Mumber 528-38-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,2 and 8 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 528-38:
(5*5)+(4*2)+(3*8)+(2*3)+(1*8)=71
71 % 10 = 1
So 528-38-1 is a valid CAS Registry Number.
528-38-1Relevant academic research and scientific papers
Coerced photodimerization reaction in the solid state through amine salt formation
Ito, Yoshikatsu,Kitada, Tetsuya,Horiguchi, Masahiro
, p. 7323 - 7329 (2007/10/03)
Photodimerization of fumaric or several γ-form trans-cinnamic acids proceeded successfully in the solid state through amine salt formation with ammonia or some aromatic heterocyclic amines (especially, imidazole). It appears that this success is due to a small size or a planar structure of the amine. A layered or a channel-type clathrate crystal structure was revealed, respectively.
Regioselective photodimerization of cinnamic acid in a micellar solution
Nakamura, Yushin
, p. 477 - 478 (2007/10/02)
Irradiation of trans-cinnamic acid (1) and its methyl ester (2) in 1% aq. cetyltirmethylammonium bromide gave dimeric products in 35 and 29% yields as a mixture of truxinic and truuxillic acids in a ratio of 19 : 1 and 3.8 : 1, respectively, while in homogeneous solutions (1) gave no photodimers and (2) gave dimeric products in 2.3% yield under similar reaction conditions.
