52800-47-2

Usage

Uses

Used in Cosmetic and Skincare Industry:
3-(benzyloxy)benzene-1,2-diol is used as a skin lightening and brightening agent for its ability to inhibit the enzyme tyrosinase, which is involved in the production of melanin. This makes it a promising ingredient for the treatment of hyperpigmentation and skin discoloration.
Used in Fragrance Industry:
3-(benzyloxy)benzene-1,2-diol is used as a fragrance ingredient due to its aromatic properties, adding a pleasant scent to various cosmetic and skincare products.
Used in Pharmaceutical Industry:
3-(benzyloxy)benzene-1,2-diol is used for its potential antiseptic and antifungal properties, making it a candidate for the development of new medications to combat infections and fungal growth.
Used in Sunscreen Formulations:
3-(benzyloxy)benzene-1,2-diol is used as an ingredient in sunscreen formulations due to its ability to absorb UV radiation, providing protection against harmful ultraviolet rays and reducing the risk of skin damage and premature aging.

Upstream product

• 100-39-0 benzyl bromide 
• 87-66-1 2-hydroxyresorcinol 
• 103215-00-5 4-(benzyloxy)-2-ethoxybenzo[d][1,3]dioxole 
• 100-44-7 benzyl chloride 
• 103214-99-9 2-ethoxy4-hydroxy-1,3-benzodioxol 

Downstream Products

• 103215-06-1 3'-benzyloxybenzo-15-crown-5 
• 52249-83-9 1-(benzyloxy)-2,3-dimethoxybenzene 
• 103215-01-6 1-Benzyloxy-2,3-bis<2-hydroxyethoxy>benzol 
• 535967-55-6 2,3-bis(2'-methoxyethoxy)-1-benzyloxybenzene 
• 535967-60-3 2,3-bis(2'-(2''-(2'''-methoxyethoxy)ethoxy)ethoxy)-1-benzyloxybenzene 
• 913985-88-3 4-bromo-2,3-dimethoxy-1-benzyloxybenzene 
• 913985-90-7 N-[2-(4-hydroxy-2,3-dimethoxy-phenyl)-ethyl]-acetamide 
• 770686-91-4 4-benzyloxy-2,3-dimethoxyphenethylamine 
• 913985-89-4 N-[2-(4-benzyloxy-2,3-dimethoxy-phenyl)-ethyl]-acetamide 
• 69471-04-1 4-benzyloxy-2,3-dimethoxybenzaldehyde 
• 19587-73-6 2.3-Dimethoxy-4-benzyloxy-benzylalkohol 
• 5150-42-5 2,3-dimethoxyphenol 
• 3117-02-0 2,3-dimethoxy-1,4-benzoquinone 
• 103215-05-0 3'-benzyloxybenzo-18-crown-6 

Relevant academic research and scientific papers

BIOMARKER PANEL TARGETED TO DISEASES DUE TO MULTIFACTORIAL ONTOLOGY OF GLYCOCALYX DISRUPTION

The present disclosure provides biomarkers useful as companion diagnostics for detecting glycocalyx-based disease that is amenable to treatment using compounds designed for improving the condition of the glycocalyx and/or reducing inflammation and/or oxidative damage, as well as related compositions, kits, and methods.

Chemoselective reactions of 3-Benzyloxy-1,2-o-Quinone with organometallic reagents

Chemoselective additions of organometallic reagents to 3-benzyloxy-1,2-o- quinone are described. Various nucleophiles are shown to undergo selective 1,2-addition, 1,4-addition, and etherification. Selective 1,2-additions provide stable, nondimerizing o-quinols as a novel alternative to oxidative dearomatization.

Synthesis of photochromic benzopyrans annulated by 15(18)-crown-5(6) ether

The reaction of hydroxy-substituted benzo-15(18)-crown-5(6) ether or benzo-18-crown-6 ether with β-phenylcinnamaldehyde in the presence of titanium tetraethoxide yielded crown-annulated 2,2-diphenylbenzopyrans. The compounds are photochromic, and the spectral characteristics of their colored form are unusual for this class of chromenes.

Monofunctionalization of phenolic hydroxy onto a polyphenol

A region-specific monofunctionalization of a phenolic hydroxy onto a polyphenol for the preparation of a compound of the formula STR1 wherein R is selected from the group consisting of hydrogen, alkyl of 1 to 8 carbon atoms, alkenyl and alkynyl of 2 to 8

Synthesis and Characterization of Crowned 1,4-Benzoquinones as Ionophore-Dienophile (Redox) Combined Systems: Double Interaction with Catecholamines and Tryptamine

The crowned 1,4-benzoquinones (1) (15-crown-5) and (2) (18-crown-6) have been synthesized from pyrogallol (3) by: (1) the selective monobenzylation (4); (2) crown ether formation using a pyrocatechols (5) and (6); (3) debenzylation (7) and (8); and (4) oxidation to 1,4-benzoquinones.Both compounds (1) and (2) underwent smooth Diels-Alder reactions with cyclopentadiene (25 deg C), thebaine (80 deg C), and buta-1,3-diene (BF3*Et2O, 0 deg C).The cyclopentadiene adducts (11) and (12) were photochemically transformed into the cage compounds (13) and (14), while the thebaine adducts (15) and (16) were smoothly converted into the hydroquinone derivatives (17) and (18) by silicic acid.The butadiene adducts (19) and (20) were transformed into the crowned naphthoquinones (23) and (24) in high yields.The redox potentials of these crowned quinones in the presence of alkali-metal ions were studied by cyclic voltammetry.The specific interaction between compound (2) and tryptamine, dopamine, and homoveratrylamine via ion-binding and charge-transfer complex formation was evidenced by u.v. spectroscopic studies.

Chinone von Benzo- und Dibenzokronenethern

The preparation of the 1,4-quinones of benzocrown-5 (1), benzocrown-6 (2), and dibenzocrown-6 (3) and their quinols is described.The quinones are obtained by Fremy salt oxidation of the corresponding 3-hydroxybenzo-crown ethers which are readily accessible by a double protective group synthesis from 1,2,3-trihydroxybenzene.The synthetic pathway also provides a general high yield preparation of 2,3-dialkoxy-1,4-benzoquinones.The new crown ethers are characterised by 1H- and 13C-N.M.R. as well as U.V. spectroscopy.Non-aqueous redox potentials aredetermined by cyclic voltammetry.Crystalline complexes of 1 and 2 with various ammonium, alkali, and alkaline earth cations are also described.

3-Hydroxy-3-(1,2,5-thiadiazolyloxyalkanol)-3,4-dihydro-2H-1,5-benzodioxepin products

3-Hydroxy-3-(substituted-aminoalkyl-3,4-dihydro-2H-1,5-benzodioxepin products are described that exhibit ≈-advenergic stimulating properties and are therefore suitable for use as bronchodilating agents. The products are prepared essentially by four princi