52808-07-8Relevant academic research and scientific papers
Labelled compounds of potential biological interest. V. Preparation of some hypolipidemic agents labelled with tritium
Gosztonyi,Bondesson,Domeij,Stjernstrom
, p. 231 - 238 (1978)
Two hypolipidemic aryloxyacetic acid derivatives and one aryloxymethylmalonic acid derivative were labelled with tritium in the aryloxy moiety. The corresponding phenols were first labelled by the Yavorsky method and then transformed to the desired products by synthetic reaction steps. For comparative pharmacokinetic and metabolic studies the carboxylic acid corresponding to clofibrate was also labelled by the same procedure.
