Journal of labelled compounds and radiopharmaceuticals p. 231 - 238 (1978)
Update date:2022-07-29
Topics:
Gosztonyi
Bondesson
Domeij
Stjernstrom
Two hypolipidemic aryloxyacetic acid derivatives and one aryloxymethylmalonic acid derivative were labelled with tritium in the aryloxy moiety. The corresponding phenols were first labelled by the Yavorsky method and then transformed to the desired products by synthetic reaction steps. For comparative pharmacokinetic and metabolic studies the carboxylic acid corresponding to clofibrate was also labelled by the same procedure.
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